222 results found
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    H3K27 modifications define segmental regulatory domains in the Drosophila bithorax complex

    Sarah K Bowman et al.
    Segment-specific boundaries of histone modifications reveal the regulatory logic of a classic developmental control region.
    1. Ecology
    2. Evolutionary Biology

    Evolution of thorax architecture in ant castes highlights trade-off between flight and ground behaviors

    Roberto A Keller et al.
    Body shape and behavioural specializations found across the castes of ant species evolved together and reflect different abilities for ground behaviors.
    1. Stem Cells and Regenerative Medicine

    Trithorax maintains the functional heterogeneity of neural stem cells through the transcription factor Buttonhead

    Hideyuki Komori et al.
    The Drosophila equivalent of the human protein Mixed Lineage Leukemia 1n enables neural stem cells to generate neural progenitors through the fly equivalent of the human transcription factor Sp8, thereby contributing to an increased number and diversity of cell types during brain development.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Atrophin controls developmental signaling pathways via interactions with Trithorax-like

    Kelvin Yeung et al.
    ChIP-seq and phenotypic analyses reveal Atrophin from Drosophila directly regulates Notch and Dpp signaling components, and engrailed gene expression, via interactions with GAGA Factor.
    1. Physics of Living Systems
    2. Developmental Biology

    Unified quantitative characterization of epithelial tissue development

    Boris Guirao et al.
    A new approach measures the respective participations of elementary cell behaviors – such as cell division, intercalation, shape change and death – in the shaping of animal tissues.
    1. Developmental Biology

    The Hippo effector Yorkie activates transcription by interacting with a histone methyltransferase complex through Ncoa6

    Yun Qing et al.
    Elucidating the molecular mechanism by which the Hippo signaling effector Yorkie (Yki) functions as a transcriptional coactivator in growth control reveals the importance of a histone-modifying enzyme for this process.
    1. Developmental Biology

    Neuron hemilineages provide the functional ground plan for the Drosophila ventral nervous system

    Robin M Harris et al.
    Hemilineages link neuronal stem cells to behavioral functions by providing a conserved ground plan of neuronal types that evolution then uses to sculpt different types of walking and flight behaviors.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Elba, a novel developmentally regulated chromatin boundary factor is a hetero-tripartite DNA binding complex

    Tsutomu Aoki et al.
    A chromatin boundary factor that is only active during early embryo development has been discovered in Drosophila.

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