Molecular, cellular and behavioral genetic approaches in Platynereis dumerilii indicate that r-Opsins can act as ancient, light-dependent modulators of mechanosensation, and suggest that light-independent mechanosensory roles of r-Opsins evolved secondarily.

Selective forces imposed by the squid animal host drive rapid adaptation of non-native Vibrio fischeri bacteria through convergent mutations of large effect, unmasking preexisting coordinated regulation of symbiosis.

Serum response factor (SRF) deficient reactive astrocytes are neuroprotective in the mammalian brain.

Combinatorial signaling leads to transcription factor co-localization at Rev-erb sensitive enhancers, enabling a diversified cellular response to complex stimuli.

Intracellular and interorgan skeletal crosstalk highlights integrative skeletal physiology.

Sleep-wake patterns, together with a suprachiasmatic nuclei-independent circadian factor, are necessary and sufficient to maintain high-amplitude nychthemeral rhythms in PERIOD-2.

Drosophila melanogastereven-skipped enhancers control transcriptional bursting by modulating frequency and amplitude, regardless of varying transcription factor inputs, even when mutated to express in embryonic regions not under selective pressure.

RNA profiles from lungs of mice exposed to intermittent hypoxia shared similarity with gene expression changes in human lung from patients with pulmonary diseases, including pulmonary hypertension, COPD, and asthma.

Light signals adjusting the brain's daily clock induce distinct waveform changes in molecular clock gene rhythms at dawn and dusk, and trigger regionally differential clock changes.

Cellular NAD+ levels change during stage conversion and regulate function of a novel transcription factor that controls developmental switching in the human pathogen Entamoeba histolytica.