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    1. Neuroscience

    Intermittent subthalamic nucleus deep brain stimulation induces risk-aversive behavior in human subjects

    Shaun R Patel et al.
    Deep brain stimulation can selectively modify neural activity within the subthalamic nucleus to modify decisions under uncertainty in human subjects.
    1. Neuroscience

    Rapid whole brain imaging of neural activity in freely behaving larval zebrafish (Danio rerio)

    Lin Cong et al.
    The integration of a novel high spatiotemporal resolution volume imaging technique and a fast 3D tracking system allows capturing whole brain neural activities in a freely behaving larval zebrafish.
    1. Developmental Biology
    2. Neuroscience

    A novel perivascular cell population in the zebrafish brain

    Marina Venero Galanternik et al.
    A new brain perivascular cell type in the zebrafish related to mammalian Fluorescent Granular Perithelial (FGP) cells emerges directly from endothelium during early development.
    1. Developmental Biology
    2. Neuroscience

    Transverse sinus injections drive robust whole-brain expression of transgenes

    Ali S Hamodi et al.
    A new viral injection method targets the transverse sinuses to achieve robust whole-brain delivery of single or multiple genes in multiple mammalian species early in development.
    1. Stem Cells and Regenerative Medicine
    2. Neuroscience

    Adult axolotls can regenerate original neuronal diversity in response to brain injury

    Ryoji Amamoto et al.
    Upon injury, the regeneration of the adult axolotl brain rebuilds neuronal diversity, but alters the original long-distance circuitry and tissue architecture.
    1. Immunology and Inflammation
    2. Neuroscience

    Internalization and presentation of myelin antigens by the brain endothelium guides antigen-specific T cell migration

    Melissa A Lopes Pinheiro et al.
    Antigen-specific control of CD4+ T cell trans-migration by brain endothelial cells via presentation of CNS-derived antigens in MHC-II molecules.
    1. Developmental Biology
    2. Neuroscience

    Delivery of circulating lipoproteins to specific neurons in the Drosophila brain regulates systemic insulin signaling

    Marko Brankatschk et al.
    Yeast specific lipids promote the transport of lipid transfer protein (LTP) across the blood brain barrier to the neurons that regulate systemic insulin signaling.
    1. Neuroscience

    GABA, not BOLD, reveals dissociable learning-dependent plasticity mechanisms in the human brain

    Polytimi Frangou et al.
    Combining GABA with fMRI measurements in the human brain uncovers distinct suppression mechanisms that optimize perceptual decisions through learning and experience-dependent plasticity in the visual cortex.
    1. Cancer Biology
    2. Neuroscience

    Brain tumours repurpose endogenous neuron to microglia signalling mechanisms to promote their own proliferation

    Kelda Chia et al.
    P2ry12-mediated microglial interactions stimulate the proliferation of brain tumour initiating cells.
    1. Developmental Biology

    Suppression of transcytosis regulates zebrafish blood-brain barrier function

    Natasha M O'Brown et al.
    The zebrafish has been established as a genetic and molecular model for the blood-brain barrier.