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Specific amino acids in the N-terminus of the replication initiator protein DnaA inhibit translation elongation upon carbon starvation, illustrating that the identity of the N-terminal amino acids of a protein can modulate protein synthesis yield under changing conditions.

High-resolution live imaging reveals how and when the mouse heart first starts to beat during development and how the onset of beating impacts on heart muscle cell maturation and heart formation.

A gene network analysis approach reveals a conserved small regulatory RNA that is crucial for bacterial cell survival across distinct stress conditions.

A nonspecific cation current mediated by TRPM4 channels is a major contributor to the increase in excitability induced by cholinergic modulation in hippocampal CA1 pyramidal neurons, which are thought to play an important role in episodic memory.

Quantitative live-cell time-lapse imaging reveals that the spatial and temporal degree of cortical polarity domains reflects stem-cell division capacity in cells of the Arabidopsis plant leaf epidermis.

Glycosylation of flagellins with pseudaminic acid in the bacterial cytoplasm governed by an unknown type of modular glycosyltransferase harboring an N-terminal substrate binding domain and a C-terminal glycosyltransferase domain.

A proteomics-based approach identifies novel substrate proteins of the Lon protease in Caulobacter crescentus and reveals a critical role of Lon in regulating flagella assembly and stalk biogenesis during the cell cycle.

PAR-3/Baz function is regulated by CDK1 in asymmetrically dividing cells in the central and peripheral nervous system of Drosophila revealing direct regulation of cell polarity by the cell cycle machinery in the context of cell fate specification.

Morphogenetic forces from tissue invagination orient cell division through a previously undescribed mechanism of force-dependent LGN/Pins polarization.