222 results found
    1. Cell Biology
    2. Developmental Biology

    Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

    Patricia Giselle Cipriani, Olivia Bay ... Kristin C Gunsalus
    Two novel LOTUS-domain proteins are core germ granule components that directly recruit Caenorhabditis elegans Vasa, regulate germ granule size and localization, and provide an organizational framework for ribonucleoprotein complexes.
    1. Neuroscience

    Development of a Marmoset Apparatus for Automated Pulling to study cooperative behaviors

    Olivia C Meisner, Weikang Shi ... Steve WC Chang
    The Marmoset Apparatus for Automated Pulling provides a powerful and scalable experimental platform for studying behavioral and neural mechanisms underlying cooperation in freely moving marmosets.
    1. Cell Biology

    Mitochondrial Homeostasis: Auto-regulation in the powerhouse

    Helena M Viola, Livia C Hool
    Mitochondrial flashes have a central role in ensuring that ATP levels remain constant in heart cells.
    Version of Record
    Insight
    1. Neuroscience

    What the success of brain imaging implies about the neural code

    Olivia Guest, Bradley C Love
    For brain imaging to be useful despite its limitations in measuring neural activity, the neural code must be smooth both in a traditional sense and functionally.
    1. Structural Biology and Molecular Biophysics
    2. Biochemistry and Chemical Biology

    Structural mechanism of ligand activation in human calcium-sensing receptor

    Yong Geng, Lidia Mosyak ... Qing R Fan
    L-amino acids are agonists of calcium-sensing receptor, and act jointly with calcium and phosphate ions to control receptor function.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Introgression of regulatory alleles and a missense coding mutation drive plumage pattern diversity in the rock pigeon

    Anna I Vickrey, Rebecca Bruders ... Michael D Shapiro
    Different kinds of molecular changes at one genetic locus control different feather pigmentation patterns, and the darkest patterns resulted from hybridization with another species.
    1. Computational and Systems Biology
    2. Neuroscience

    Combining hypothesis- and data-driven neuroscience modeling in FAIR workflows

    Olivia Eriksson, Upinder Singh Bhalla ... Jeanette Hellgren Kotaleski
    Increased usability and validity of neuroscience models, through FAIR workflows for the whole modeling process, including data and model management, parameter estimation, uncertainty quantification, and model analysis.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    The E2 Marie Kondo and the CTLH E3 ligase clear deposited RNA binding proteins during the maternal-to-zygotic transition

    Michael Zavortink, Lauren N Rutt ... Olivia S Rissland
    In fruit flies, maternally deposited RNA-binding proteins are removed during the maternal-to-zygotic transition via a mechanism of translational upregulation of Kondo, the key E2 enzyme, at egg activation.
    1. Cell Biology
    2. Immunology and Inflammation

    Apoptosis recognition receptors regulate skin tissue repair in mice

    Olivia Justynski, Kate Bridges ... Valerie Horsley
    After an injury to the skin, murine wounds upregulate apoptosis and efferocytosis pathways, which are required for effective healing and may similarly impact wound healing in diabetic patients.
    1. Ecology

    Naïve individuals promote collective exploration in homing pigeons

    Gabriele Valentini, Theodore P Pavlic ... Takao Sasaki
    Ephemeral leadership between differently experienced birds regulates the balance between exploration and exploitation over successive homing flights in a manner that facilitates the accumulation of route innovations.

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