By comparing gene expression in people before and after they received the influenza vaccine, researchers were able to identify genes that contribute to differences in individual responses to vaccination.

Mechanistic insights show how treatment with apoA1 is anti-inflammatory by rapidly disrupting macrophage chemotaxis and monocyte recruitment.

Eukaryotic chemotaxis to live bacteria was quantified at a high throughput level, for the first time, and mechanistically examined for the interrelationship between chemotaxis and phagocytosis.

The threonine kinase controls maternal mRNA translation phosphorylate components of the translational machinery, including translational repressors, which appear to inactivate to promote the oocyte-to-embryo transition.

The H+ influx coupled to nutrient uptake and the plasma membrane H+-ATPase are central actors of the activation of target of rapamycin complex 1 (TORC1) in budding yeast Saccharomyces cerevisiae..

By controlling the SUMOylation of the protein CAR-1, the aging-regulating pathways downstream of the Insulin/IGF signaling cascade and of the germ cells of the nematode Caenorhabditis elegans are integrated.

The complement pathway can contribute to corneal sensation loss and nerve damage during ocular surface inflammation.

Efficient dedifferentiation is characterized by robustness to mutation, flexibility in ordering of cellular events and reversal of developmental changes along a single gene expression trajectory.

Transcriptome analysis of mouse brain revealed that the APOE4 allele and sex can alter air pollution neurotoxicity in adults.

Single cell transcriptomics reveal a complex orchestration of lung immune cells during the transition from fetal to air-breathing life to fill context-specific functions in tissue remodeling, angiogenesis, and immunity.