19 results found
    1. Cell Biology

    A FRET-based study reveals site-specific regulation of spindle position checkpoint proteins at yeast centrosomes

    Yuliya Gryaznova, Ayse Koca Caydasi ... Gislene Pereira
    Daughter-cell-associated factors and centrosome-based regulation is important in mitotic exit and spindle position checkpoint control.
    1. Cell Biology

    Protein phosphatase 1 in association with Bud14 inhibits mitotic exit in Saccharomyces cerevisiae

    Dilara Kocakaplan, Hüseyin Karabürk ... Ayse Koca Caydasi
    PP1-Bud14 is a novel Spindle Position Checkpoint component.
    1. Neuroscience

    Mechanistic insights into a TIMP3-sensitive pathway constitutively engaged in the regulation of cerebral hemodynamics

    Carmen Capone, Fabrice Dabertrand ... Anne Joutel
    Extracellular matrix signaling constitutively regulates cerebral blood flow in both physiological and pathological settings.
    1. Epidemiology and Global Health

    Building resilient cervical cancer prevention through gender-neutral HPV vaccination

    Irene Man, Damien Georges ... Iacopo Baussano
    Shifting from girls-only to gender-neutral HPV vaccination strategy improves the resilience of cervical cancer prevention and enhances progress towards cervical cancer elimination.
    1. Developmental Biology
    2. Evolutionary Biology

    Conservation of peripheral nervous system formation mechanisms in divergent ascidian embryos

    Joshua F Coulcher, Agnès Roure ... Sébastien Darras
    Developmental regulatory mechanisms for peripheral nervous system formation appear to be conserved in ascidians despite extensive genomic divergence after 390 MY of separate evolution.
    1. Cell Biology

    Spatial signals link exit from mitosis to spindle position

    Jill Elaine Falk, Dai Tsuchiya ... Angelika Amon
    In yeast, exit from mitosis is triggered by the movement of one spindle pole body out of the mother cell into the bud, the future daughter cell.
    1. Neuroscience

    Assessment of neurovascular coupling and cortical spreading depression in mixed mouse models of atherosclerosis and Alzheimer’s disease

    Osman Shabir, Ben Pendry ... Jason Berwick
    Mice modelling atherosclerosis show neurovascular breakdown in the cortex compared to healthy controls, and inducing atherosclerosis in mice modelling Alzheimer's disease increases the number of amyloid plaques in the hippocampus.
    1. Cell Biology
    2. Developmental Biology

    Discovery of novel determinants of endothelial lineage using chimeric heterokaryons

    Wing Tak Wong, Gianfranco Matrone ... John P Cooke
    Bioinformatic analysis of gene expression in chimeric heterokaryons can identify novel regulators of cell lineage.
    1. Genetics and Genomics
    2. Evolutionary Biology

    The Primate Major Histocompatibility Complex: An Illustrative Example of Gene Family Evolution

    Alyssa Lyn Fortier, Jonathan K Pritchard
    Not revised
    Reviewed Preprint v1
    1. Cancer Biology
    2. Structural Biology and Molecular Biophysics

    Conserved regulatory motifs in the juxtamembrane domain and kinase N-lobe revealed through deep mutational scanning of the MET receptor tyrosine kinase domain

    Gabriella O Estevam, Edmond M Linossi ... James S Fraser
    Deep mutational scanning reveals interactions in the MET kinase domain that are critical for regulation and cancer-related signaling.

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