48 results found
    1. Microbiology and Infectious Disease

    Inhibiting host-protein deposition on urinary catheters reduces associated urinary tract infections

    Marissa Jeme Andersen, ChunKi Fong ... Ana L Flores-Mireles
    The use of liquid-infused catheters results in significant reduction of bladder and catheter colonization, systemic dissemination, and bladder inflammation in a clinically relevant mouse model of CAUTI by targeting host-protein deposition on the urinary catheter.
    1. Neuroscience

    Lactate is an energy substrate for rodent cortical neurons and enhances their firing activity

    Anastassios Karagiannis, Thierry Gallopin ... Bruno Cauli
    Lactate is preferred to glucose as an energy substrate and exacerbates spiking activity in most neuron types of juvenile somatosensory cortex by closing ATP-sensitive potassium channels.
    1. Microbiology and Infectious Disease

    Effect of SARS-CoV-2 proteins on vascular permeability

    Rossana Rauti, Meishar Shahoha ... Ben Meir Maoz
    A specific SARS-CoV-2 proteins that affect the vascular permeability and impairs the functionality of other significant organs has been identified.
    1. Neuroscience

    Astrocyte aquaporin mediates a tonic water efflux maintaining brain homeostasis

    Cuong Pham, Yuji Komaki ... Dongdong Li
    The water channel AQP4 contributes to a tonic water outflow from brain astrocytes, thereby modulating their volume dynamics and the ambient water homeostasis.
    1. Neuroscience

    Elevated pyramidal cell firing orchestrates arteriolar vasoconstriction through COX-2-derived prostaglandin E2 signaling

    Benjamin Le Gac, Marine Tournissac ... Bruno Cauli
    Not revised
    Reviewed Preprint v1
    1. Epidemiology and Global Health

    Estimating effectiveness of case-area targeted response interventions against cholera in Haiti

    Edwige Michel, Jean Gaudart ... Stanislas Rebaudet
    Case-area targeted interventions conducted by rapid response teams appeared significantly effective to mitigate and shorten local cholera outbreaks in the Centre department of Haiti in 2015-2017.
    1. Genetics and Genomics
    2. Evolutionary Biology

    The recombination landscape of introgression in yeast

    Enrique J Schwarzkopf, Nathan Brandt, Caiti Smukowski Heil
    Revised
    Reviewed Preprint v2
    Updated
    1. Neuroscience

    Centrally expressed Cav3.2 T-type calcium channel is critical for the initiation and maintenance of neuropathic pain

    Sophie L Fayad, Guillaume Ourties ... Nathalie Leresche
    Specific deletion of Cav3.2 channels in anterior pretectal neurons reduced mechanical and cold allodynia, pointing to Cav3.2 channels as prime targets to develop innovative analgesic pharmacology that will not only act at the peripheral level but also in central structures.
    1. Biochemistry and Chemical Biology
    2. Ecology

    Sex-specific triacylglycerides are widely conserved in Drosophila and mediate mating behavior

    Jacqueline SR Chin, Shane R Ellis ... Joanne Y Yew
    Triacylglycerides found in the males of 11 species of Drosophila form a largely overlooked, novel, sex-specific class of pheromones that act to suppress courtship behaviour.
    1. Neuroscience

    Cell type specificity of neurovascular coupling in cerebral cortex

    Hana Uhlirova, Kıvılcım Kılıç ... Anna Devor
    Excitatory and inhibitory cortical neurons drive parallel vasodilatory pathways, while vasoconstriction is mediated exclusively by inhibition acting via Neuropeptide Y binding to Y1 receptors.

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