Discovery and initial characterization of a conserved small protein translated from a transcript annotated as a human long non-coding RNA.

Directed evolution of the resistance enzyme Cfr under antibiotic selection identifies increased Cfr expression and stability as strategies to boost resistance and reveals that Cfr modification of the ribosome confers resistance by sterically occluding binding of antibiotics.

CRISPR/Cas9 engineered locus-specific proteomics leads to the identification of NuRD, CAF-1, and MBD3L2 as regulators of the early embryonic transcription factor DUX4.

A single protein catalyzes site-specific DNA recombination upon blue-light illumination.

Mutual suppression of ETV1 by Capicua (CIC) and ETS2 repressor factor (ERF) limits prostate cancer progression.

The integrated analysis of multi-omics and functional evidence both in vitro and in knock-in mouse models reveal novel gain-of-function pathogenic mechanisms of dominant CRX HD missense mutations.

CBFs, the central regulators of low-temperature signaling, have a function to directly activate the expression of COOLAIR, an antisense RNA of FLC, during vernalization process, but COOLAIR is not required for the vernalization response.

The common post-translational modification trans-4-hydroxy-L-proline is reversed by gut microbes with the help of hydroxyproline dehydratase (HypD), an enzyme that performs a radical chemical mechanism.

Serum response factor (SRF) deficient reactive astrocytes are neuroprotective in the mammalian brain.

A novel transgenic rat for studying the role of specific corticotropin-releasing factor type-1 receptor-expressing cell populations in physiology and behavior.