5,215 results found
    1. Cell Biology

    ScRNA-seq and scATAC-seq reveal that sertoli cell mediate spermatogenesis disorders through stage-specific communications in non-obstructive azoospermia

    Shimin Wang, Hongxian Wang ... Dong Zhao
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    • Incomplete
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state

    Ruben Sebastian-Perez, Shoma Nakagawa ... Maria Pia Cosma
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    PROTAC-induced Protein Structural Dynamics in Targeted Protein Degradation

    Kingsley Y Wu, Ta I Hung, Chia-en A Chang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology

    Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects

    Kayleigh Bozon, Hartmut Cuny ... Sally L Dunwoodie
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Solid
    1. Neuroscience

    Synchronous processing of temporal information across the hippocampus, striatum, and orbitofrontal cortex

    Akihiro Shimbo, Yukiko Sekine ... Shigeyoshi Fujisawa
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Evolutionary Biology

    Large inversions in Lake Malawi cichlids are associated with habitat preference, lineage, and sex determination

    Nikesh M Kumar, Taylor L Cooper ... Patrick T McGrath
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Incomplete
    1. Neuroscience

    Cortical dynamics in hand/forelimb S1 and M1 evoked by brief photostimulation of the mouse’s hand

    Daniela Piña Novo, Mang Gao ... Gordon MG Shepherd
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Cell Biology

    Testosterone-Induced Metabolic Changes in Seminal Vesicle Epithelial cells Alter Plasma Components to Enhance Sperm Fertility

    Takahiro Yamanaka, Zimo Xiao ... Masayuki Shimada
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Genetics and Genomics
    2. Cancer Biology

    Combinatorial CRISPR screen reveals FYN and KDM4 as targets for synergistic drug combination for treating triple negative breast cancer

    Tackhoon Kim, Byung-Sun Park ... Timothy K Lu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Supralinear dendritic integration in murine dendrite-targeting interneurons

    Simonas Griesius, Amy Richardson, Dimitri Michael Kullmann
    NMDA receptors mediate prominent supralinear summation of clustered excitatory inputs to the dendrites of neurogliaform and oriens-lacunosum moleculare interneurons of the hippocampus, showing that these cells perform sub-cellular computations.
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