Innate lymphoid cells, which are dynamic under steady-state conditions, respond to a colitogenic stimulus by mobilizing from cryptopatches and secreting GM-CSF to organize the pro-inflammatory response.
LSD induces a pattern of changed global brain connectivity characterized by hypo-connectivity in associative areas and hyper-connectivity across sensory and somatomotor areas that is dependent on the serotonin 2A receptor.
The general principles that underlie the mechanism of action of the COP9-Signalosome, a key regulator of the largest family of ubiquitin ligase enzymes in human cells, have been identified using structural and kinetic techniques.
In large vaccine trials conducted in dengue-endemic Asia and Latin America, the CYD-TDV tetravalent dengue vaccine shows limited variation in intra-serotype efficacy in the target population for vaccination (>9 years).
Toddlers with autism spectrum disorders have alterations in gaze patterns together with frequency specific network atypicalities between key brain areas of the social brain when freely exploring naturalistic and ecologically valid dynamic social stimuli.