Skip to Content
eLife home page
Submit my research
(via ORCID - An ORCID is a persistent digital identifier for researchers)
Browse the search results
Page 2 of 345
Immunology and Inflammation
Atypical memory B-cells are associated with
anemia through anti-phosphatidylserine antibodies
Juan Rivera-Correa et al.
The association of atypical memory B-cells and autoimmune antibodies (anti-phosphatidylserine) with hemoglobin levels in malaria patients uncovers a novel mechanism for the human malaria-induced anemia previously identified in mice.
Computational and Systems Biology
Immunology and Inflammation
An evolutionary recent IFN/IL-6/CEBP axis is linked to monocyte expansion and tuberculosis severity in humans
Murilo Delgobo et al.
exploits an IFN/IL6/CEBP axis linked to monocyte expansion in humans.
Structural Biology and Molecular Biophysics
Ligand recognition and gating mechanism through three ligand-binding sites of human TRPM2 channel
Yihe Huang et al.
High-resolution structures of human TRPM2 in different functional states provided the mechanism underlying ligand recognition, channel activation and inhibition.
Defined neuronal populations drive fatal phenotype in a mouse model of Leigh syndrome
Irene Bolea et al.
Glutamatergic brainstem neurons drive motor and respiratory deficits, and GABAergic basal ganglia neurons cause hypothermia and fatal epileptic events, in a model of mitochondrial disease.
Human Biology and Medicine
Stimulation of Piezo1 by mechanical signals promotes bone anabolism
Xuehua Li et al.
Mechanical stimuli activate Piezo1 in osteoblast lineage cells and thereby promote bone formation in part via Wnt1.
Activity dynamics of amygdala GABAergic neurons during cataplexy of narcolepsy
Ying Sun et al.
Deep brain calcium imaging reveals the abnormal neuronal activity patterns of the amygdala GABAergic neurons in an animal model of human sleep disorder narcolepsy.
A primal role for the vestibular sense in the development of coordinated locomotion
David E Ehrlich, David Schoppik
Zebrafish use their sense of gravity and their cerebellum to coordinate the fin and body movements that, as they develop, allow them to better maintain balance as they climb.
Chromosomes and Gene Expression
Translational regulation of protrusion-localized RNAs involves silencing and clustering after transport
Konstadinos Moissoglu et al.
RNAs enriched at cell protrusions are translated regardless of their location in the cytoplasm but are dynamically repressed in retracting protrusions and incorporated into heterogeneous RNA clusters.
Genetics and Genomics
Neuronal TORC1 modulates longevity via AMPK and cell nonautonomous regulation of mitochondrial dynamics in
Yue Zhang et al.
Modulating the nutrient sensor TORC1 only in neurons in
is sufficient to regulate systemic longevity via inter-tissue signals that remodel mitochondria networks in non neuronal cells.
MicroRNA-mediated control of developmental lymphangiogenesis
Hyun Min Jung et al.
Lymphatic-enriched microRNA miR-204 is required for lymphatic development through its effects on the key lymphatic transcription factor NFATC1.
Be the first to read new articles from eLife
Sign up for alerts
Please leave this field empty
Back to top