333 results found
    1. Developmental Biology

    Planar cell polarity coordination in a cnidarian embryo provides clues to animal body axis evolution

    Julie Uveira, Antoine Donati ... Tsuyoshi Momose
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Neuroscience

    Deficiency of orexin receptor type 1 in dopaminergic neurons increases novelty-induced locomotion and exploration

    Xing Xiao, Gagik Yeghiazaryan ... Anne Christine Hausen
    Ox1R signaling in dopaminergic neurons regulates context-induced locomotor activity and exploration in mice.
    Version of Record
    Short Report
    • Valuable
    • Solid
    1. Cell Biology
    2. Cancer Biology

    Cell crowding induces TRPV4 inhibition and its relocation to plasma membranes, implicating pro-invasive cell volume reduction mechanotransduction pathway

    Xiangning Bu, Nathanael Ashby ... Inhee Chung
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    TRPV4 overactivation enhances cellular contractility and drives ocular hypertension in TGFβ2 overexpressing eyes

    Christopher N Rudzitis, Monika Lakk ... David Križaj
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Neuroscience

    Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells

    Dominic Gonschorek, Matías A Goldin ... Thomas Euler
    Nitric oxide is a type-selective neuromodulator affecting the temporal, but not the spatial response kinetics of a specific subset of mouse retinal ganglion cells.
    1. Neuroscience

    High-resolution awake mouse fMRI at 14 tesla

    David Hike, Xiaochen Liu ... Xin Yu
    High-resolution blood oxygen level-dependent functional magnetic resonance imaging enables brain-wide mapping of activated regions during sensory stimulation in awake mice, including associated areas, for high-order sensory processing including anticipation responses.
    1. Neuroscience

    Multi-dimensional oscillatory activity of mouse GnRH neurons in vivo

    Su Young Han, Shel-Hwa Yeo ... Allan E Herbison
    The gonadotropin-releasing hormone (GnRH) neurons controlling fertility exhibit abrupt increases in activity to generate luteinizing hormone (LH) pulses and a sustained oscillatory pattern of activity to generate the LH surge.
    1. Cell Biology
    2. Neuroscience

    Psychological stress disturbs bone metabolism via miR-335-3p/Fos signaling in osteoclast

    Jiayao Zhang, Juan Li ... Weicai Liu
    miR-335-3p, which targets FOS and inhibits its activation of NFATC1 signaling, is an important regulator for osteoclast function and responsible for the psychological stress-induced osteoporosis.
    1. Genetics and Genomics

    DYRK1A kinase triplication is the major cause of Otitis Media in Down Syndrome

    Hilda Tateossian, Amy Southern ... Steve DM Brown
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Neuroscience

    Rab10 regulates neuropeptide release by maintaining Ca2+ homeostasis and protein synthesis

    Jian Dong, Miao Chen ... Matthijs Verhage
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
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