333 results found
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin

    Martina Brunati, Simone Perucca ... Luca Rampoldi
    Hepsin is the first protease identified to modulate specific cleavage and secretion of a Zona Pellucida domain protein, uromodulin.
    1. Neuroscience

    Mapping responses to focal injections of bicuculline in the lateral parafacial region identifies core regions for maximal generation of active expiration

    Annette Pisanski, Mitchell Prostebby ... Silvia Pagliardini
    Multivariate analysis of respiratory cycle shows that GABAergic disinhibition in the rostral regions of the lateral parafacial area is linked to the most significant and enduring changes in active expiration.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences

    Raeann Goering, Laura I Hudish ... J Matthew Taliaferro
    The molecular determinants for neuronal subcellular RNA transport by FMRP are defined, with interactions between RNA G-quadruplexes and the RGG domain of FMRP being of critical importance.
    1. Neuroscience

    Rabphilin-3A negatively regulates neuropeptide release, through its SNAP25 interaction

    Adlin Abramian, Rein I Hoogstraaten ... Matthijs Verhage
    Live imaging at single-vesicle resolution reveals rabphilin-3A as the first identified negative regulator of neuropeptide release in mammalian neurons.
    Version of Record
    Research Article
    • Important
    • Convincing
    • Incomplete
    1. Neuroscience

    Direct translation of climbing fiber burst-mediated sensory coding into post-synaptic Purkinje cell dendritic calcium

    Seung-Eon Roh, Seung Ha Kim ... Sang Jeong Kim
    Purkinje cell dendritic calcium response is finely controlled by the burst activity of climbing fiber during sensory coding.
    1. Neuroscience

    Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells

    Dominic Gonschorek, Matías A Goldin ... Thomas Euler
    Nitric oxide is a type-selective neuromodulator affecting the temporal, but not the spatial response kinetics of a specific subset of mouse retinal ganglion cells.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structural characterization of NrnC identifies unifying features of dinucleases

    Justin D Lormand, Soo-Kyoung Kim ... Holger Sondermann
    Dinucleases, specialized enzymes that catalyze the final step in RNA degradation, have evolved independently and repeatedly to fulfill essential roles in cell growth.
    1. Neuroscience

    CB1-receptor-mediated inhibitory LTD triggers presynaptic remodeling via protein synthesis and ubiquitination

    Hannah R Monday, Mathieu Bourdenx ... Pablo E Castillo
    CB1-receptor-mediated inhibitory long-term depression (LTD) relies on both protein synthesis and ubiquitination to elicit structural changes that underlie long-term reduction of GABA release.
    1. Cell Biology
    2. Neuroscience

    Sorting nexin-27 regulates AMPA receptor trafficking through the synaptic adhesion protein LRFN2

    Kirsty J McMillan, Paul J Banks ... Peter J Cullen
    An unbiased proteomic approach identifies a new regulator of AMPA receptor trafficking providing additional insight into synaptic transmission and plasticity.
    1. Cell Biology
    2. Neuroscience

    Functional interdependence of the actin nucleator Cobl and Cobl-like in dendritic arbor development

    Maryam Izadi, Eric Seemann ... Michael M Kessels
    Extended biochemical and functional analyses in primary neurons show that early neuronal morphogenesis critically relies on cooperation of the actin nucleator Cobl and its ancestor Cobl-like and uncover their cooperative mechanisms at dendritic branch initiation sites.

Refine your results by:

Type
Research categories