Shigehiro Namiki, Michael H Dickinson ... Gwyneth M Card
Systematic analysis of descending neuron anatomy reveals the basic functional map of descending sensory-motor pathways in flies and provides genetic tools for targeted interrogation of neural circuits.
The Trrap-HAT-Sp1 axis operates a conserved transcriptional program to control proper microtubule dynamics in brain homeostasis and prevents neurodegeneration.
Biochemical and cell biology studies reveal that postsynaptic density condensates of neuronal synapses and actin cytoskeletons can directly communicate with each other in a phase separation-dependent manner.
Richard CV Tyser, Antonio MA Miranda ... Paul R Riley
High-resolution live imaging reveals how and when the mouse heart first starts to beat during development and how the onset of beating impacts on heart muscle cell maturation and heart formation.
The TRPM4 ion channel has been identified as an important component in the causation of mechanical pressure overload-induced pathological left ventricular hypertrophy, which is a powerful predictor of cardiovascular mortality.