A new open-source computational toolbox for processing in vivo microendoscopic calcium imaging data performs signal demixing and denoising much more accurately than previously available methods, significantly improving the utility of this imaging modality.

Loss of membrane-bound ICAM-1, overexpression of soluble ICAM-1 or ILKAP activity in tumor cells induce resistance to antigen-specific cytotoxic T-cell-mediated killing independently from regulating antigen presentation, PD-L1 expression, IFN-γ, or TNF-α responsiveness.

Ponto-spinal CRH neurons in Barrington’s nucleus are a core component of an inferential circuit that regulates autonomous micturition and generates voids when the bladder is full.

TRIM23 plays a critical role in the switching from early to late adipogenic enhanceosomes by stabilizing the PPARγ protein.

A comprehensive molecular characterization of Schlemm’s canal cells to date provides a wealth of molecular details.

RIM binding UNC-13L C2A domain releases UNC-13L from an autoinhibitory homodimeric complex to become fusion-competent, and regulates probability of synaptic vesicle release in the post-priming process.

Unveiling the circuit organization and functional roles of endopiriform neurons projecting to the ventral CA1.

In a mouse model of Parkinson's disease, deep brain stimulation of the subthalamic nucleus disrupts movement-related neural activity in parallel with relieving motor symptoms.

The direct interaction of R-type Ca²⁺ channel Cav2.3 and GABA_B receptor auxiliary subunits in the active zone of medial habenula terminals scales synaptic strength independent of GABA_B receptor activation.