24 results found
    1. Neuroscience

    Ultrastructural sublaminar-specific diversity of excitatory synaptic boutons in layer 1 of the adult human temporal lobe neocortex

    Astrid Rollenhagen, Akram Sadeghi ... Joachim HR Lübke
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    • Incomplete
    1. Neuroscience

    A novel monomeric amyloid β-activated signaling pathway regulates brain development via inhibition of microglia

    Hyo Jun Kwon, Devi Santhosh, Zhen Huang
    Molecular genetics identifies a novel microglial pathway essential for mouse brain development and a previously unknown anti-inflammatory activity of monomeric amyloid β that activates this pathway.
    1. Developmental Biology
    2. Neuroscience

    Spatiotemporal changes in Netrin/Dscam1 signaling dictate axonal projection direction in Drosophila small ventral lateral clock neurons

    Jingjing Liu, Yuedong Wang ... Yao Tian
    Dynamic local microenvironments in Drosophila facilitate axonal projection direction transitions in the absence of clear landmarks.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Deciphering molecular heterogeneity and dynamics of human hippocampal neural stem cells at different ages and injury states

    Junjun Yao, Shaoxing Dai ... Tianqing Li
    A single-nucleus transcriptomic atlas reveals the molecular signatures and trajectory dynamics of the neurogenic lineage in the human hippocampus during neonatal development, adulthood, aging, and after injury.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons

    Ayumu Mubuchi, Mina Takechi ... Shinji Miyata
    The extracellular matrix formed during embryonic brain development facilitates the migration of cortical neurons.
    1. Developmental Biology
    2. Neuroscience

    Temporal transcriptomic dynamics in developing macaque neocortex

    Longjiang Xu, Zan Yuan ... Xiaozhong Peng
    A useful single-cell resource provides the prenatal macaque different cell types’ gene expression profiles in the parietal cerebral cortex lobe.
    1. Developmental Biology
    2. Neuroscience

    The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes

    Xiong Yang, Rong Wan ... Ke Tang
    Two intrinsic factors converge to govern the differentiation and integration of distinct characteristics of the hippocampus in mice.
    1. Developmental Biology
    2. Neuroscience

    Lmx1a is a master regulator of the cortical hem

    Igor Y Iskusnykh, Nikolai Fattakhov ... Victor V Chizhikov
    LIM-homeodomain transcription factor Lmx1a co-regulates multiple developmental processes in the cortical hem, a major signaling center necessary for hippocampus formation in the mammalian brain.
    1. Developmental Biology
    2. Neuroscience

    Transcriptional profiling of sequentially generated septal neuron fates

    Miguel Turrero García, Sarah K Stegmann ... Corey C Harwell
    A combination of single-cell RNA sequencing of the developing septum and genetic fate mapping is used to analyze the origin of septal neurons.
    1. Developmental Biology
    2. Neuroscience

    Dentate gyrus development requires a cortical hem-derived astrocytic scaffold

    Alessia Caramello, Christophe Galichet ... Robin Lovell-Badge
    An astrocytic scaffold that depends on SOX9 guides embryonic neuronal progenitors toward the developing dentate gyrus.

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