Skip to Content
eLife home page
Submit my research
(via ORCID - An ORCID is a persistent digital identifier for researchers)
Browse the search results
Page 3 of 7
Modulation of anxiety and fear via distinct intrahippocampal circuits
Elif Engin et al.
The hippocampus features a double dissociation in its circuits with respect to the regulation of fear and anxiety, with CA3 and the dentate gyrus implicated in anxiety and CA1 in fear.
An extrasynaptic GABAergic signal modulates a pattern of forward movement in
Yu Shen et al.
The activity of a set of GABAergic neurons is causally linked with a locomotory pattern in moving animals, and the mechanisms underlying the neuromodulatory role of GABA are illuminated.
Biochemistry and Chemical Biology
Structural Biology and Molecular Biophysics
Lis1 regulates dynein by sterically blocking its mechanochemical cycle
Katerina Toropova et al.
Structural and functional studies reveal how a ubiquitous regulator of dynein keeps the microtubule-based motor in a persistent track-bound state.
mutation leads to genomic instability in prostate cancer
Gunther Boysen et al.
mutations underlie a novel, genomically unstable subclass of prostate cancer by altering DNA repair.
Anatomical and functional organization of the human substantia nigra and its connections
Yu Zhang et al.
The human substantia nigra can be parcellated into three subdivisions that subserve emotional, cognitive and somatomotor function.
Physics of Living Systems
Self-organized patterning of cell morphology via mechanosensitive feedback
Natalie A Dye et al.
Radial patterns of cell morphology in the
larval wing emerge through mechanosensitive dynamics of cell polarity.
Immunology and Inflammation
T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1
Yujiao He et al.
T-cell receptor signaling actively regulates gating of the nuclear pore complex (NPC) in T cells by inducing translocation of protein kinase C-θ to the NPC to promote the sumoylation of RanGAP1.
A rapid whisker-based decision underlying skilled locomotion in mice
Richard A Warren et al.
A rapid whisker-based decision underlies skilled locomotion in mice largely independent of cerebral cortex.
Microbiology and Infectious Disease
Septal secretion of protein A in
requires SecA and lipoteichoic acid synthesis
Wenqi Yu et al.
Surface protein precursors traffic to lipoteichoic acid-rich septal membranes of
for cleavage of their YSIRK-GXXS motif signal peptides and SecA-mediated translocation across the plasma membrane.
Immunology and Inflammation
Long-term antigen exposure irreversibly modifies metabolic requirements for T cell function
Marie Bettonville et al.
Long-term exposure to recipient's alloantigens promotes major metabolic defects in T cells that are independent of PD-1-mediated regulation.
Be the first to read new articles from eLife
Sign up for email alerts
Back to top