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    1. Microbiology and Infectious Disease

    Expression of different L1 isoforms of Mastomys natalensis papillomavirus as mechanism to circumvent adaptive immunity

    Yingying Fu, Rui Cao ... Daniel Hasche
    Cutaneous papillomaviruses potentially escape humoral immune response by synthesizing an alternative major capsid protein isoform during the initial course of infection that is unable to induce neutralizing antibodies.
    1. Cancer Biology
    2. Chromosomes and Gene Expression

    Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation

    Wesley L Cai, Jocelyn Fang-Yi Chen ... Qin Yan
    The chromatin regulator WDR5 is a regulator of translation, and small molecule inhibitors or degraders of WDR5 can be used to treat triple-negative breast cancer.
    1. Chromosomes and Gene Expression

    Checkpoint inhibition of origin firing prevents inappropriate replication outside of S-phase

    Mark C Johnson, Geylani Can ... Philip Zegerman
    The S-phase checkpoint has roles in all phases of the cell cycle, which has implications for the majority of cancers that lack cell cycle controls.
    1. Genetics and Genomics

    Base editing strategies to convert CAG to CAA diminish the disease-causing mutation in Huntington’s disease

    Doo Eun Choi, Jun Wan Shin ... Jong-Min Lee
    Uninterrupted CAG repeat length determines onset age in Huntington's disease, and therefore, base editing strategies to generate CAA interruption offer new therapeutic opportunities as they diminish the disease-causing mutation.
    1. Neuroscience

    Internally generated time in the rodent hippocampus is logarithmically compressed

    Rui Cao, John H Bladon ... Marc W Howard
    Receptive fields for time in the hippocampus, like receptive fields for retinal space and receptive fields for numerosity, obey the Weber-Fechner law.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Radiocarbon and genomic evidence for the survival of Equus Sussemionus until the late Holocene

    Dawei Cai, Siqi Zhu ... Yu Jiang
    The first nuclear genomes of the Equus (Sussemionus) ovodovi enable us to reconstruct the speciation and extinction trajectory of this lineage.
    1. Neuroscience

    Group III metabotropic glutamate receptors gate long-term potentiation and synaptic tagging/capture in rat hippocampal area CA2

    Ananya Dasgupta, Yu Jia Lim ... Sreedharan Sajikumar
    Group III metabotropic glutamate receptor inhibition facilitates synaptic plasticity in the plasticity-resistant synapses of hippocampal area CA2, a brain region critical for social memory.
    1. Physics of Living Systems

    Flower-like patterns in multi-species bacterial colonies

    Liyang Xiong, Yuansheng Cao ... Lev Tsimring
    Mechanical interactions between bacterial species with different motility characteristics play an important role in spatial-temporal dynamics of multi-species bacterial colonies and can lead to formation of complex patterns.
    1. Microbiology and Infectious Disease

    Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway

    Rebecca CS Edgar, Ghizal Siddiqui ... Tania F de Koning-Ward
    Plasmodium falciparum aminopeptidase PfA-M17 is essential to parasite survival and plays a role in hemoglobin digestion, providing a rationale for further development of inhibitors against this enzyme.
    1. Neuroscience

    A spatial-attentional mechanism underlies action-related distortions of time judgment

    Liyu Cao
    The distribution of visuospatial attention shapes the timing report results obtained with the Libet clock method, thus explaining the temporal binding effect in this context.