Functional ultrasound imaging was used to monitor brain hemodynamics and sensory-evoked thalamocortical functions in awake rats pre- and post-stroke, advancing our understanding toward new therapeutic developments.

Proximity-labeling using engineered biotin ligases TurboID and miniTurbo enables detection of cell-type-specific and low abundance protein complexes and subcellular proteomes in Arabidopsis and other plants.

Choice history signals bias the interpretation of current sensory input, akin to shifting endogenous attention toward (or away from) the previously selected interpretation.

Coordinated microRNAs activity induced by VEGF represses cell proliferation and favors cell migration at the onset of sprouting angiogenesis in endothelial cells.

GapR-seq enables the global mapping of positive supercoiling in bacteria and yeast, revealing positive supercoils downstream of highly expressed genes and, in yeast, associated with centromeres, pericentromeres, telomeres, replication origins, and R-loops.

Definition of leukemia gene expression mechanisms reveals general principles of cancer gene control and offers a pharmacologic strategy for its therapeutic reprogramming.

Single cell expression data can be used to determine how regulatory transcription factors and target genes are connected, and is especially useful when studying transcription factors controlling heterogeneous cell states.

Live imaging of the Notch co-activator Mastermind reveals that it promotes the formation of a dynamic transcription hub in Notch ON nuclei, conferring probabilistic transcription and providing a template for signal memory.

Cell-cycle-dependent Notch signaling cooperates with temporal transcription factors to promote the progression of the temporal transcription factor cascade in Drosophila medulla neuroblasts.