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Two novel subsets of microglia identified by their unique autofluorescence profiles differ in their subcellular organization, proteomic signatures and in their response to aging and lysosomal dysfunction.

A photoswitchable pore blocker was covalently attached to a cysteine-substituted glutamate delta 2 receptor, to provide optical control of its ion channel function.

Single nuclei RNA sequencing unmasks 16 variants of midbrain dopamine neurons within a continuum of their gene expression landscape and resolves their differential vulnerability.

Excitatory and inhibitory postsynaptic receptors are maintained at corresponded postsynaptic sites with the different dependency of presynaptic neurons in the mature mammalian brain.

Neurexins are presynaptic adhesion molecules in the serotonin system which regulate neuron survival and serotonin neuromodulation through active zone formation and serotonin release.

A G1 cyclin shows key properties expected of a protein that could link cell cycle progression to cell growth.

A guide summarizing the diversity of cell types in the parabrachial nucleus.

Quantitative analysis of time-dependent transcription data elucidates the signal processing within the genetic network that regulates transcriptional cell cycle oscillations in yeast.

Cell type-specific transcriptomics in energy homeostasis neurons has identified hundreds of genes and multiple signaling pathways that are regulated by weight loss in mice, as well as several previously unexamined genes that can regulate appetite and body weight.