1,717 results found
    1. Genetics and Genomics

    Dynamics and regulatory roles of RNA m6A methylation in unbalanced genomes

    Shuai Zhang, Ruixue Wang ... Lin Sun
    Global analyses using aneuploid Drosophila revealed the dynamic roles of RNA m6A modification in regulating gene expression and development under genomic imbalance, highlighting its potential relationships with dosage-related effects.
    1. Developmental Biology

    Comprehensive profiling of migratory primordial germ cells reveals niche-specific differences in non-canonical Wnt and Nodal-Lefty signaling in anterior vs posterior migrants

    Rebecca G Jaszczak, Jay W Zussman ... Diana J Laird
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Developmental Biology

    Meioc-Piwil1 complexes regulate rRNA transcription for differentiation of spermatogonial stem cells

    Toshihiro Kawasaki, Toshiya Nishimura ... Noriyoshi Sakai
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Solid
    1. Genetics and Genomics
    2. Neuroscience

    Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus

    Akanksha Bafna, Gareth Banks ... Patrick M Nolan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology

    TET2-mediated epigenetic modification promotes stress senescence of pancreatic β cells in type 2 diabetes mellitus

    Weijuan Cai, Qingqing Song ... Liang Yin
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Developmental Biology
    2. Neuroscience

    Dual role of FOXG1 in regulating gliogenesis in the developing neocortex via the FGF signalling pathway

    Mahima Bose, Ishita Talwar ... Shubha Tole
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Global transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in Pseudomonas aeruginosa

    Jiadai Huang, Yue Sun ... Xin Deng
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Chromosomes and Gene Expression

    Sir2 and Fun30 regulate ribosomal DNA replication timing via MCM helicase positioning and nucleosome occupancy

    Carmina Lichauco, Eric J Foss ... Antonio Bedalov
    Precocious ribosomal DNA replication in sir2 mutants requires Fun30.
    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    Human eIF2A has a minimal role in translation initiation and in uORF-mediated translational control

    Mykola Roiuk, Marilena Neff, Aurelio A Teleman
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Stem Cells and Regenerative Medicine

    Chromatin activity of IκBα mediates the exit from naïve pluripotency

    Luis G Palma, Daniel Álvarez-Villanueva ... Anna Bigas
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
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