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    1. Immunology and Inflammation

    Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses

    Shiho Chiba et al.
    An immune system pattern recognition receptor potentiates anti-tumor innate immune responses, offering new insight into anti-tumor activity of the innate immune system.
    1. Biochemistry and Chemical Biology
    2. Ecology

    Sex-specific triacylglycerides are widely conserved in Drosophila and mediate mating behavior

    Jacqueline SR Chin et al.
    Triacylglycerides found in the males of 11 species of Drosophila form a largely overlooked, novel, sex-specific class of pheromones that act to suppress courtship behaviour.
    1. Structural Biology and Molecular Biophysics
    2. Evolutionary Biology

    Methylation at the C-2 position of hopanoids increases rigidity in native bacterial membranes

    Chia-Hung Wu et al.
    Methylation specifically enhances the ability of hopanoids to rigidify membranes under physiologically relevant conditions, which impacts the current interpretation of the 2-methylhopane fossil record.
    1. Cell Biology

    The equatorial position of the metaphase plate ensures symmetric cell divisions

    Chia Huei Tan et al.
    Human cells center the position of the metaphase plate before anaphase onset to ensure the formation of equal-sized daughter cells.
    1. Human Biology and Medicine
    2. Neuroscience

    A homozygous loss-of-function CAMK2A mutation causes growth delay, frequent seizures and severe intellectual disability

    Poh Hui Chia et al.
    A biallelic missense mutation in the highly conserved, neuron-specific kinase CAMK2A abrogates holoenzyme assembly and causes a new inherited neurodevelopmental disease.
    1. Neuroscience

    Distinct stages of synapse elimination are induced by burst firing of CA1 neurons and differentially require MEF2A/D

    Chia-Wei Chang et al.
    Increasing periods of neuronal activity progressively weaken and then eliminate synapses through the activation of specific transcription factors and genes.
    1. Ecology
    2. Evolutionary Biology

    Extreme adaptations for aquatic ectoparasitism in a Jurassic fly larva

    Jun Chen et al.
    Well-preserved fossils reveal an extreme morphological specialization of fly larvae, and broaden our understanding of the diversity of ectoparasitism in Mesozoic insects.
  1. Interview: Going places

    Moving from China to the US to do a postdoc is part of Huan Yan's plan to have his own lab one day.
  2. Repeating the message: an interview with Yunsheng Cheng

    Yunsheng Cheng grew up in a village in Anhui Province in China and received his bachelor's degree from Anhui Normal University. He is currently a graduate student at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, where he studies how neurons transmit signals to other cells. He enjoys listening to country music, and after he graduates he would like to pursue postdoctoral training abroad.