39 results found
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Modes of flagellar assembly in Chlamydomonas reinhardtii and Trypanosoma brucei

    Johanna L Höög et al.
    Comparative electron tomography of growing flagellar tips reveals that axonemal growth differs between short and long flagella, and between species.
    1. Plant Biology

    Phosphoprotein SAK1 is a regulator of acclimation to singlet oxygen in Chlamydomonas reinhardtii

    Setsuko Wakao et al.
    SAK1, a novel cytoplasmic phosphoprotein, is a key intermediate component of the retrograde signaling pathway controlling nuclear gene expression during acclimation of Chlamydomonas cells to singlet oxygen stress.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Vesicles: Looking inside the cell

    Eric C Arakel, Blanche Schwappach
    Advances in imaging techniques have shed new light on the structure of vesicles formed by COPI protein complexes.
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    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis

    Michael Taschner et al.
    CRISPR/Cas knockout of intraflagellar transport protein 80 shows that this subunit is absolutely required for ciliogenesis, and biophysical studies reveal that this protein may dimerize the intraflagellar transport complex.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins

    Katja Gotthardt et al.
    The ciliary G-protein Arl13B – which is often mutated in Joubert syndrome – is the Guanine nucleotide exchange factor for the G-protein Arl3 and exclusively localizes to cilia.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    The structure of the COPI coat determined within the cell

    Yury S Bykov et al.
    Cryo-electron tomography of COPI vesicles in the Golgi reveals coat structure, disassembly dynamics, cargo binding, and morphological variability.
    1. Ecology

    Endosymbiosis: Gasping for air

    Steven G Ball, Ugo Cenci
    Transcriptomics is shedding new light on the relationship between photosynthetic algae and salamander eggs.
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    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Intraflagellar transport: Trainspotting in a cilium

    Dhivya Kumar, Stephen M King
    A new imaging technique sheds light on how cilia regulate their length and growth.
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    1. Physics of Living Systems
    2. Microbiology and Infectious Disease

    Phototaxis: Life in focus

    Carol Dieckmann, Telsa Mittelmeier
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    1. Cell Biology

    IFT trains in different stages of assembly queue at the ciliary base for consecutive release into the cilium

    Jenna L Wingfield et al.
    Multimegadalton intraflagellar transport (IFT) trains assemble by sequential recruitment of IFT subcomplexes from the cell body to the ciliary basal bodies and tubulin, the main IFT cargo, is loaded briefly before trains depart.

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