34 results found
    1. Neuroscience

    Position of UNC-13 in the active zone regulates synaptic vesicle release probability and release kinetics

    Keming Zhou et al.
    The precise position of UNC-13 at the active zone near a synapse depends on the N-terminus of the protein, and the C2A domain in particular, and is essential for accelerating neurotransmitter release.
    1. Physics of Living Systems

    Upper bound on the biological effects of 50/60 Hz magnetic fields mediated by radical pairs

    PJ Hore
    Any effects of environmental 50/60 Hz magnetic fields on human biology due to a radical pair mechanism should be no more dangerous than those incurred by travelling a few kilometres.
    1. Neuroscience

    Bed nucleus of the stria terminalis regulates fear to unpredictable threat signals

    Travis D Goode et al.
    The bed nucleus of the stria terminalis (BNST) is required for the expression of defensive behavior to uncertain threats, a function that is central to pathological anxiety.
    1. Cell Biology

    The cell proliferation antigen Ki-67 organises heterochromatin

    Michal Sobecki et al.
    Antigen Ki-67, which is widely used as a cell proliferation marker, controls heterochromatin organisation and gene expression.
    1. Human Biology and Medicine
    2. Neuroscience

    A Cryptochrome 2 mutation yields advanced sleep phase in humans

    Arisa Hirano et al.
    A missense mutation in the human Cryptochrome 2 (CRY2) gene leads to the condition of familial advanced sleep phase.
    1. Neuroscience

    Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors

    Romain Durand-de Cuttoli et al.
    In vivo deconstruction of reward-related behaviors with circuit and pharmacological specificity using designer, light-controllable nicotinic acetylcholine receptors.
    1. Neuroscience

    The β-alanine transporter BalaT is required for visual neurotransmission in Drosophila

    Yongchao Han et al.
    BalaT-dependent β-alanine trafficking pathway in retinal pigment cells is critical for maintaining synaptic transmission of photoreceptor neurons in Drosophila.
    1. Genetics and Genomics

    Generation of a versatile BiFC ORFeome library for analyzing protein–protein interactions in live Drosophila

    Johannes Bischof et al.
    Generation of a new fly line library for analysing protein–protein interactions in vivo.
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Guanylate binding proteins directly attack Toxoplasma gondii via supramolecular complexes

    Elisabeth Kravets et al.
    Cellular immunity against Toxoplasma parasites is orchestrated by GBP complexes attacking the parasite membrane.
    1. Neuroscience

    The impact of bilateral ongoing activity on evoked responses in mouse cortex

    Daisuke Shimaoka et al.
    Spontaneous bilateral fluctuations add with evoked cortical activity and explain much of the variability in sensory responses.

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