94 results found
    1. Neuroscience

    Genetic and pharmacologic alterations of claudin9 levels suffice to induce functional and mature inner hair cells

    Yingying Chen, Jeong Han Lee ... Ebenezer N Yamoah
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    1. Computational and Systems Biology

    Statistical analysis supports pervasive RNA subcellular localization and alternative 3' UTR regulation

    Rob Bierman, Jui M Dave ... Julia Salzman
    Analysis of genome-wide spatial transcriptomics data reveals cell-type specific subcellular RNA localization, and a subset of genes show significantly high correlation between spatial patterning and 3' UTR length.
    1. Cell Biology

    Rho-ROCK liberates sequestered claudin for rapid de novo tight junction formation

    Yuma Cho, Akari Taniguchi ... Junichi Ikenouchi
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Lacticaseibacillus rhamnosus P118 enhances host tolerance to Salmonella infection by promoting microbe-derived indole metabolites

    Baikui Wang, Xianqi Peng ... Min Yue
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    1. Medicine
    2. Immunology and Inflammation

    Inhibition on neutrophil extracellular traps by oligomeric procyanidins alleviate chemotherapy-induced chronic kidney injury via gut-kidney axis

    Yaqi Luan, Weiwei He ... Rong Wang
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Immunology and Inflammation

    Exercise training at different intensities induces heat stress, disrupts barrier function and alters microbiota in the gut of mice

    Puqiao Lian, Artemiy Kovynev ... Saskia Braber
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease

    Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway

    Xin Ma, Li Meng ... Xinyan Han
    Revised
    Reviewed Preprint v4
    Updated
    • Valuable
    • Solid
    1. Cancer Biology

    FABP4-mediated lipid accumulation and lipolysis in tumor-associated macrophages promote breast cancer metastasis

    Matthew Yorek, Xingshan Jiang ... Bing Li
    FABP4 plays a central role in driving the formation lipid-laden macrophages induced by unsaturated fats and enhances macrophage-tumor interactions, thereby promoting breast cancer migration and metastasis.
    1. Cell Biology
    2. Neuroscience

    Neurons enhance blood–brain barrier function via upregulating claudin-5 and VE-cadherin expression due to glial cell line-derived neurotrophic factor secretion

    Lu Yang, Zijin Lin ... Li Liu
    The established triple co-culture blood-–brain barrier (BBB) model could be used for predicting drugs’ BBB permeability, and co-culture with neurons and astrocytes enhanced brain endothelial cells’ integrity by secreting GDNF, which upregulated claudin-5 and VE-cadherin expression.
    1. Cancer Biology

    Loss function of tumor suppressor FRMD8 confers resistance to tamoxifen therapy via a dual mechanism

    Weijie Wu, Miao Yu ... Hongquan Zhang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
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