A new soma-targeted variant of the large-conductance blue-light-sensitive opsin CoChR combined with advanced optical stimulation methods allows high-efficiency all-optical neuronal imaging and stimulation in mouse brain in vivo.

Generation of stable transgenic opsin lines together with in vivo calibration of their efficacy using behavioural and electrophysiological assays constitutes a novel optogenetic toolkit in zebrafish.

A one-photon three-dimensional light sculpture technique has been developed and demonstrated for high spatio-temporal resolution photostimulation and imaging of dozens of neurons in the intact mouse brain in vivo.

A discrete population of genetically accessible pretectal neurons controls visually guided hunting behaviour in larval zebrafish.

Bioluminescence monitoring and selective silencing in zebrafish larva reveal a novel sensorimotor circuit modulating speed in the moving spinal cord.

Glutamatergic signaling from the lateral hypothalamus instructs lateral habenular neurons for encoding aversive external stimuli to subsequently guide escape behaviours.

Simultaneous quantification of each of the main motor programs in the roundworm C. elegans yields new insights into the neural mechanisms that coordinate animal behavior.

Age-related tendon degeneration is initiated by loss of tenocytes associated with synthesis of high-turnover rate proteoglycans and glycoproteins.

Pairs of spinal cord neurons arising from a shared progenitor get input from and make outputs to mostly different synaptic partners.

By differentially modulating the two major excitatory inputs to the striatum, mu- and delta-opioid receptors regulate the balance between thalamic and cortical inputs to the striatum.