249 results found
    1. Microbiology and Infectious Disease
    Mosquito infection by gametocytes from cultures exposed to dihydroartemisinin (DHA) from Figure 2, Portugaliza et al.

    Malaria: A Collection of Articles

    Edited by Olivier Silvie et al.
    eLife has recently published a wide range of papers on malaria, covering a diversity of themes including parasite biology, epidemiology, immunology, drugs and vaccines.
    1. Developmental Biology

    A gradient of Wnt activity positions the neurosensory domains of the inner ear

    Magdalena Żak, Nicolas Daudet
    Manipulations of Wnt signalling in the chicken embryo reveal how it controls in a dose-dependent manner the formation of the neurosensory territories of the early developing inner ear.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Deep sampling of Hawaiian Caenorhabditis elegans reveals high genetic diversity and admixture with global populations

    Tim A Crombie et al.
    Hawaiian Caenorhabditis elegans harbor high levels of genetic diversity that might represent the complex patterns of ancestral diversity in the species prior to human influence.
    1. Developmental Biology

    DNA methylation and gene expression changes derived from assisted reproductive technologies can be decreased by reproductive fluids

    Sebastian Canovas et al.
    Reproductive fluids help the correct establishment of some epigenetic marks and gene expression in preimplantation pig embryos.
    1. Neuroscience

    Transformation of spatiotemporal dynamics in the macaque vestibular system from otolith afferents to cortex

    Jean Laurens et al.
    The spatial and dynamic properties of self-motion signals are acquired at the first stage of otolith signal transformation, which is in the brainstem and cerebellum, and conserved across brainstem, cerebellar and cortical areas.
    1. Cancer Biology

    Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice

    Alessandro Bitto et al.
    Three months treatment with the drug rapamycin increases lifespan, alters cancer prevalence, remodels the microbiome, and improves functional measures of health in middle aged mice in a dose- and sex-dependent manner.
    1. Neuroscience

    Odor-identity dependent motor programs underlie behavioral responses to odors

    Seung-Hye Jung et al.
    Flies respond to odors by modulating multiple independently modulated motor programs.
    1. Cell Biology
    2. Immunology and Inflammation

    Diverse stimuli engage different neutrophil extracellular trap pathways

    Elaine F Kenny et al.
    NETs induction, a central component of the innate immune response, utilises assorted signalling pathways as demonstrated through the analysis of healthy and patient neutrophils treated with five distinct stimuli.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    The target of the DEAH-box NTP triphosphatase Prp43 in Saccharomyces cerevisiae spliceosomes is the U2 snRNP-intron interaction

    Jean-Baptiste Fourmann et al.
    Prp43 binds to the pre-mRNA and contacts predominantly U2 proteins in the budding yeast spliceosome.
    1. Computational and Systems Biology
    2. Neuroscience

    Direction-dependent arm kinematics reveal optimal integration of gravity cues

    Jeremie Gaveau et al.
    Theoretical models and experimental results reveal how the optimal integration of gravity cues fine tunes movement kinematics so that motor effort is minimized in the ubiquitous gravity field.

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