5,808 results found
    1. Ecology
    2. Evolutionary Biology
    C. elegans illustration

    The Natural History of Model Organisms: C. elegans outside the Petri dish

    Lise Frézal, Marie-Anne Félix
    To leverage the tools, resources and knowledge that exist for C. elegans so that we can study ecology, evolution and other aspects of biology, we need to understand the natural history of this important model organism.
    1. Medicine

    Ankyrin-G mediates targeting of both Na+ and KATP channels to the rat cardiac intercalated disc

    Hua-Qian Yang et al.
    The functional interaction of Na+ and KATP channels at the intercalated disk of cardiomyocytes depends on Ankyrin G and is clinically relevant since KATP channel mutations affect Na+ channel expression.
    1. Developmental Biology

    Muscle-derived Myoglianin regulates Drosophila imaginal disc growth

    Ambuj Upadhyay et al.
    A Drosophila myostatin-like factor provides an extrinsic signal produced by muscles that regulates Drosophila appendage development.
    1. Immunology and Inflammation

    p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle

    Hui Che et al.
    A novel IVDD mechanism that involves p16 is demonstrated and theoretical evidence is provided for effective methods to downregulate p16 and so reverse IVDD.
    1. Cell Biology
    2. Developmental Biology

    Dpp from the anterior stripe of cells is crucial for the growth of the Drosophila wing disc

    Shinya Matsuda, Markus Affolter
    A recent report proposing that the dpp stripe (the main source of the protein dpp) is dispensable for Drosophila wing disc growth missed the critical role on growth due to imprecise spatial removal of dpp.
    1. Cell Biology
    2. Developmental Biology

    Myoblast cytonemes mediate Wg signaling from the wing imaginal disc and Delta-Notch signaling to the air sac primordium

    Hai Huang, Thomas B Kornberg
    Cytonemes mediate, and are essential for, Wingless signaling from the Drosophila wing disc to disc-associated myoblasts and for Delta-Notch signaling from these myoblasts to the dorsal air sac primordium.
  1. Engendering equality: The Lise-Meitner-Gesellschaft

    The Lise-Meitner-Gesellschaft aims to raise awareness of gender inequality in the natural sciences and mathematics.
    1. Neuroscience

    Integrating prediction errors at two time scales permits rapid recalibration of speech sound categories

    Itsaso Olasagasti, Anne-Lise Giraud
    Keeping flexible adaptable representations of speech categories at different time scales allows the brain to maintain stable perception in the face of varying speech sound characteristics.

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