145 results found
    1. Neuroscience

    Reactive oxygen species regulate activity-dependent neuronal plasticity in Drosophila

    Matthew CW Oswald et al.
    Reactive oxygen species, previously considered damaging agents linked to pathology, are required for normal neuronal plasticity, including adjustment of synaptic terminal size, maintenance of synaptic physiology and adaptive behavioural responses.
    1. Neuroscience

    Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity

    Eiko Iwakoshi-Ukena et al.
    Neurosecretory protein GL, a previously unknown mammalian neuropeptide, is a novel hypothalamic factor which regulates feeding behavior and peripheral lipogenesis in animals.
    1. Neuroscience

    Efficient and accurate extraction of in vivo calcium signals from microendoscopic video data

    Pengcheng Zhou et al.
    A new open-source computational toolbox for processing in vivo microendoscopic calcium imaging data performs signal demixing and denoising much more accurately than previously available methods, significantly improving the utility of this imaging modality.
    1. Neuroscience

    A cortical disinhibitory circuit for enhancing adult plasticity

    Yu Fu et al.
    Building on previous work (Kaneko and Stryker, 2014), we report that the specific population of inhibitory neurons that increases the responses of neurons in the visual cortex during locomotion will also, when activated or blocked artificially, dramatically alter adult cortical plasticity, revealing that the aerobic exercise of locomotion is not necessary.
    1. Computational and Systems Biology
    2. Neuroscience

    Fundamental bound on the persistence and capacity of short-term memory stored as graded persistent activity

    Onur Ozan Koyluoglu et al.
    A fundamental lower-bound on memory recall precision, which declines with storage duration and number of stored items, is derived, and human performance is shown to be well-fit by this theoretical bound.
    1. Neuroscience

    Cell type-specific long-range connections of basal forebrain circuit

    Johnny Phong Do et al.
    Whole-brain mapping of the basal forebrain circuits reveals a connection diagram with highly convergent inputs and divergent outputs.
    1. Neuroscience

    Dopamine neurons projecting to medial shell of the nucleus accumbens drive heroin reinforcement

    Julie Corre et al.
    Disinhibition of dopamine neurons in the midbrain drives heroin reinforcement, the initial step towards opioid addiction.
    1. Neuroscience

    Loss of Frataxin activates the iron/sphingolipid/PDK1/Mef2 pathway in mammals

    Kuchuan Chen et al.
    The iron/sphingolipid/PDK1/Mef2 pathway is activated in mammals upon loss of Frataxin.

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