104 results found
    1. Cell Biology
    2. Developmental Biology

    The novel SH3 domain protein Dlish/CG10933 mediates fat signaling in Drosophila by binding and regulating Dachs

    Yifei Zhang et al.
    The Fat-regulated scaffolding protein Dlish controls the activity, levels and cortical localization of Warts-inhibiting myosin Dachs by linking Dachs to a critical Dachs regulator, the DHHC palmitoyltransferase Approximated, and to the Fat-mediated regulation of Dachs stability.
    1. Cell Biology
    2. Developmental Biology

    The Drosophila F-box protein Fbxl7 binds to the protocadherin Fat and regulates Dachs localization and Hippo signaling

    Justin A Bosch et al.
    The F-box protein Fbxl7 is a direct effector of the protocadherin Fat and functions in downstream pathways that regulate tissue shape and size.
    1. Developmental Biology

    Dynamic BMP signaling polarized by Toll patterns the dorsoventral axis in a hemimetabolous insect

    Lena Sachs et al.
    During the evolution of insect lineages, a signaling pathway dedicated to pathogen defense was co-opted for a new role in embryonic patterning.
    1. Structural Biology and Molecular Biophysics

    Fully automated, sequential focused ion beam milling for cryo-electron tomography

    Tobias Zachs et al.
    The automation of cryo-focused ion beam milling enables previously unfeasible cryo-electron tomography projects.
    1. Cell Biology
    2. Evolutionary Biology

    Vesicle Coat Proteins: Finding the missing link

    Thomas U Schwartz
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    1. Cell Biology
    2. Computational and Systems Biology

    Science Forum: The Human Cell Atlas

    Aviv Regev et al.
    Advances in techniques for analysing single cells and tissues have inspired an international effort to create comprehensive reference maps of all human cells - the fundamental units of life - as a basis for both understanding human health and diagnosing, monitoring and treating disease.
    1. Developmental Biology
    2. Plant Biology

    Coordination of tissue cell polarity by auxin transport and signaling

    Carla Verna et al.
    GNOM controls both auxin transport and auxin signaling to coordinate tissue cell polarity during vein patterning in plants.
    1. Developmental Biology
    2. Evolutionary Biology

    Evolution of limb development in cephalopod mollusks

    Oscar A Tarazona et al.
    Cuttlefish embryos reveal that cephalopod mollusks evolved specialized arms and tentacles by activating the same genetic circuits that control development of limbs in arthropods and vertebrates.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Transcriptome maps of general eukaryotic RNA degradation factors

    Salma Sohrabi-Jahromi et al.
    Mapping of 30 general RNA degradation factors onto the yeast transcriptome provides the global distribution of factors for RNA turnover and surveillance in a eukaryotic cell.

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