434 results found
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural characterization of encapsulated ferritin provides insight into iron storage in bacterial nanocompartments

    Didi He et al.
    Encapsulin-associated ferritin proteins form metal-dependent decamers that are active as ferroxidase enzymes, but require encapsulation to form an iron store.
    1. Neuroscience

    Cue-inhibited ventrolateral periaqueductal gray neurons signal fear output and threat probability in male rats

    Kristina M Wright et al.
    Ventrolateral periaqueductal gray neurons signal fear output through patterned inhibition of neural activity.
    1. Cell Biology
    2. Developmental Biology

    TMEM95 is a sperm membrane protein essential for mammalian fertilization

    Ismael Lamas-Toranzo et al.
    TMEM95, a protein localized to the sperm acrosome cap, is essential for fertilization.
    1. Neuroscience

    Dystroglycan is a scaffold for extracellular axon guidance decisions

    L Bailey Lindenmaier et al.
    Dystroglycan interacts with multiple partners, including the transmembrane receptor Celsr3, to regulate axon tract formation throughout the developing nervous system.
    1. Microbiology and Infectious Disease

    The human gut and groundwater harbor non-photosynthetic bacteria belonging to a new candidate phylum sibling to Cyanobacteria

    Sara C Di Rienzi et al.
    Melainabacteria, a candidate phylum related to Cyanobacteria, has been identified in gut and sediment samples by genomic analysis.
    1. Ecology
    2. Neuroscience

    Feeding-induced rearrangement of green leaf volatiles reduces moth oviposition

    Silke Allmann et al.
    The ability of Manduca moths to recognize changes in the profile of volatile compounds released by plants being attacked by Manduca caterpillars allows them to lay their eggs on plants that are less likely to be attacked by insects and other predators, and to avoid competing against other caterpillars of the same species for resources.
    1. Neuroscience

    Ventrolateral periaqueductal gray neurons prioritize threat probability over fear output

    Kristina M Wright, Michael A McDannald
    Single-unit activity in the ventrolateral periaqueductal gray, a brain region implicated in organizing fear output, is found to reflect threat probability, a more versatile threat signal.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates

    Hannah K Long et al.
    Islands of non-methylated DNA are shown to perform a similar epigenetic role in many different vertebrate species.
    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Defining host–pathogen interactions employing an artificial intelligence workflow

    Daniel Fisch et al.
    The application of deep learning fills a major gap in host–pathogen research providing for unbiased, multi-module high-throughput image analysis.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B

    Timo Vögtle et al.
    Heparan sulfates in the vessel wall bind and regulate signaling from the megakaryocyte/platelet-specific inhibitory receptor G6b-B, a critical regulator of platelet homeostasis.

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