Reoxygenation of anoxic cardiac tissue promotes massive endocytosis that is triggered by release of coenzymeA from mitochondria, followed by palmitoylation of membrane proteins, sarcolemma vesiculation, and transfer of sarolemma vesicles to large endosomes and vacuoles.

Mitochondria can trigger massive endocytosis by releasing coenzyme A into the cytoplasm and thereby promoting the addition of fatty acids to surface membrane proteins.

A comprehensive and genome-wide description of the genomic make-up and frequency of meiotic recombination in Arabidopsis thaliana reveals regional preferences, including nucleosome-free regions, and two associated recombination motifs.

The differentiation decisions made by pluripotent cells depend on their exposure to appropriate extrinsic signals and also on morphogenetic events that control receptivity to those differentiation cues.

In addition to its cytoplasmic role for translation, the seryl-tRNA synthetase also antagonizes the c-Myc transcription factor in the nucleus to transcriptionally repress the growth factor VEGFA and ensure proper development of the vasculature in vertebrates.

Orbitofrontal cortex neurons fire in response to cues with no value independent of what can be inferred through features of the predicted outcome.

Developing long bones contain distinct mesenchymal stem-cell populations derived from mesoderm and neural crest, which have specialized functions in skeleton formation and the establishment of the hematopoietic stem-cell niche, respectively.

FOXL2 maintenance of ovarian identity is not solely due to a simple direct repression of Sox9 but to the mobilization of estrogen signalling by FOXL2.

Comprehensive structural and compositional characterization of the in vivo 30S ribosomal assembly landscape reveals parallel pathways for 3′-domain formation and a previously unknown role for the assembly factor RimP.

Post-phosphoryl modification of α-dystroglycan requires the glucuronyltransferase B4GAT1; this enzyme synthesizes the acceptor glycan that serves as a primer for the glycosyltransferase LARGE to synthesize the laminin-binding glycan.