FMNL1β is phosphorylated on S1086 in a protein kinase C δ (PKCδ)-dependent manner and S1086-phosphorylated FMNL1β acts downstream of PKCδ to regulate centrosome and multivesicular bodies polarization to the immunological synapse and exosome release.

HS-AFM and Principal Component Analysis provide experimental evidence to substantiate the 'proof of principle' regarding the flexible helical twists of actin filaments that regulate the functions of actin-binding proteins.

FMNL2 associates with Formin2 and Arp2/3 complex for actin assembly, which further regulates spindle migration and INF2/Cofilin-related organelle dynamics during mammalian oocyte maturation.

Genetic and pharmacological tools are used to dissect the mechanisms by which the presynaptic actin cytoskeleton facilitates membrane internalization at synapses and, thereby, neurotransmission.

Genetic analyses reveal the importance of dynamic protein processing at the apical cell membrane in response to forces damaging cell membranes during tube expansion in tubular organs.

During tracheal morphogenesis, the scavenger receptor Emp senses and responds to luminal cargo levels by initiating apical membrane endocytosis along the longitudinal tube axis to restrict airway elongation.

FHOD1 and CARP/Ankrd1 interact with the N-terminal region of palladin and cardiomyocyte-specific deletion of palladin in adult, but not embryonic, mice leads to dilated cardiomyopathy associated with intercalated disc widening.

A highly sophisticated and adaptive interplay between modulation of myosin II function by light chain phosphorylation and environmentally controlled formin availability, is critical for a successful cytokinesis during respiratory carbohydrate metabolism in the fission yeast Schizosaccharomyces pombe.