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The 24 ANK repeats of each ankyrin are inhibited by combinatorial bindings of multiple disordered segments from their tail regions, suggesting a mechanism for differential regulations of membrane target bindings by ankyrins.

Stress fibers with multiple adhesions along their lengths and treadmilling dynamics may help migrating epithelial cells maintain a linear trajectory and thereby reinforce their collective motility.

Ecdysone-mediated regulation of Relish expression and activation in the hematopoietic niche is essential for progenitor maintenance in the Drosophila Lymph gland.

Genetic analyses reveal the importance of dynamic protein processing at the apical cell membrane in response to forces damaging cell membranes during tube expansion in tubular organs.

Adult muscle precursors (AMP) cells in Drosophila send out filopodia to interact with neighbouring muscles, which drive the reactivation of AMPs via an Insulin-Notch-Myc cascade.

Combined optogenetic and computer modeling approaches reveal how mechanical bistability of the mesoderm epithelium works jointly with apical constriction to facilitate mesoderm invagination in Drosophila, a well-characterized model for epithelial folding.

Profilin release from the filament end controls the speed of actin growth at physiological conditions.

An efficient response to DNA damage requires the assembly of actin filaments in the nucleus.

siRNA knockdown experiments reveal in detail the signaling pathway that controls cytoskeletal function during cell-in-cell invasion.

During tracheal morphogenesis, the scavenger receptor Emp senses and responds to luminal cargo levels by initiating apical membrane endocytosis along the longitudinal tube axis to restrict airway elongation.