The structure of a large enzyme complex involved in methanogenesis was determined at high resolution by electron cryo-microscopy.

A combination of direct-electron detectors and statistical movie processing allows ribosome cryo-EM structures to be determined to resolutions that were previously only attainable by X-ray crystallography.

A freely available software environment on Amazon's cloud computing network makes processing of cryo-EM data accessible and affordable.

Water molecules and amino-acid side chain rotamers have been resolved in the cryoEM structure of T20S proteasome at 2.8 angstroms.

Connectomic analysis identifies the complex circuits of a visual motion-sensing neuron that qualify them to generate direction-selective motion sensing signals using both Hassenstein-Reichardt and Barlow-Levick models.

Seipin oligomers dynamically interact with small, nascent lipid droplets near the endoplasmic reticulum to convert them into larger, mature lipid droplets in a newly identified step of lipid droplet formation.

Cryo-EM structures capture different conformational states of chromatin remodeler-nucleosome complexes.

Correlative microscopy and electron cryo-tomography on apoptotic HeLa cells reveal remodeling of outer and inner mitochondrial membranes, Bax cluster ultrastructure and ATP synthase reorganization in ruptured mitochondria.

The resolution of electron cryo-microscopy can be improved by using optimal exposure values to filter video frames.