222 results found
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Direct live imaging of cell–cell protein transfer by transient outer membrane fusion in Myxococcus xanthus

    Adrien Ducret, Betty Fleuchot ... Tâm Mignot
    Physical contact between two Myxococcus xanthus cells is sufficient to fuse their outer membrane transiently and exchange outer membrane proteins and lipids at high efficiency.
    1. Chromosomes and Gene Expression

    A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics

    Nicole A Rapicavoli, Kun Qu ... Howard Y Chang
    A long non-coding RNA regulates the expression of genes that encode proteins involved in the inflammatory response.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation

    Ji-Eun Lee, Chaochen Wang ... Kai Ge
    MLL4 (KMT2D) is a major mammalian H3K4 mono- and di-methyltransferase that is essential for enhancer activation, cell-type-specific gene expression, and cell differentiation.
    1. Chromosomes and Gene Expression
    2. Neuroscience

    The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation

    Qin Li, Sika Zheng ... Douglas L Black
    PTBP2 ensures that adult protein variants are expressed only in mature neurons through regulation of alternative splicing during early neuronal development.
    1. Developmental Biology
    2. Evolutionary Biology

    Molecular insights into the origin of the Hox-TALE patterning system

    Bruno Hudry, Morgane Thomas-Chollier ... Samir Merabet
    Interactions between Hox and TALE genes, which generate bilaterally symmetrical body plans, originated in early multicellular animals.
    1. Stem Cells and Regenerative Medicine

    Identification of a new stem cell population that generates Drosophila flight muscles

    Rajesh D Gunage, Heinrich Reichert, K VijayRaghavan
    Large flight muscle of Drosophila are made by the regulated amplification of a newly identified stem cell population.
    1. Developmental Biology

    Fringe proteins modulate Notch-ligand cis and trans interactions to specify signaling states

    Lauren LeBon, Tom V Lee ... Michael B Elowitz
    Fringe proteins modulate cis inhibitory, same-cell interactions between the Notch receptor and its ligands to control whether, and in which direction, cells can signal to one another.
    1. Neuroscience

    Synaptic organization of the Drosophila antennal lobe and its regulation by the Teneurins

    Timothy J Mosca, Liqun Luo
    A comprehensive synapse-level analysis of a fly central-brain region has led to the identification of molecules that are necessary for mediating the normal density of connections.
    1. Developmental Biology
    2. Neuroscience

    The Drosophila Sp8 transcription factor Buttonhead prevents premature differentiation of intermediate neural progenitors

    Yonggang Xie, Xiaosu Li ... Sijun Zhu
    The Drosophila equivalent of the human transcription factor Sp8 acts to ensure that neural progenitor cells undergo an appropriate number of cell divisions, thereby helping to regulate brain development and guard against tumor formation.
    1. Neuroscience

    Decoding odor quality and intensity in the Drosophila brain

    Antonia Strutz, Jan Soelter ... Silke Sachse
    The lateral horn can be classified into three functional odor response domains that decode opposing hedonic valences and odor intensity.

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