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    1. Neuroscience

    Causal roles of prefrontal cortex during spontaneous perceptual switching are determined by brain state dynamics

    Takamitsu Watanabe
    Prefrontal causal roles in bistable perception are dynamically changing and determined by the brain state to which the whole-brain activity pattern belongs.
    1. Neuroscience

    Optimization of energy state transition trajectory supports the development of executive function during youth

    Zaixu Cui, Jennifer Stiso ... Theodore D Satterthwaite
    Structural network topology develops during adolescence to facilitate activation of the fronto-parietal executive system with lower theoretical energetic cost.
    1. Neuroscience

    The neural dynamics of positive and negative expectations of pain

    Christoph Arne Wittkamp, Maren-Isabel Wolf, Michael Rose
    Pain expectation processing shifts from uniform anticipatory activation to valence-specific differentiation during sensory input.
    1. Neuroscience

    Developmental change in prefrontal cortex recruitment supports the emergence of value-guided memory

    Kate Nussenbaum, Catherine A Hartley
    The use of prior experience to adaptively prioritize information in memory increases from childhood to adulthood and engages corticostriatal circuitry.
    1. Neuroscience

    Different brain systems support learning from received and avoided pain during human pain-avoidance learning

    Marieke Jepma, Mathieu Roy ... Albert Dahan
    Pharmacological fMRI study provides evidence that learning from the unexpected presence and absence of pain is mediated by different brain systems.
    1. Genetics and Genomics
    2. Neuroscience

    Antipsychotic-induced epigenomic reorganization in frontal cortex of individuals with schizophrenia

    Bohan Zhu, Richard I Ainsworth ... Javier González-Maeso
    Age and antipsychotic treatment effects on chromatin organization in the frontal cortex of schizophrenia subjects.
    1. Neuroscience

    Recruitment of the default mode network during a demanding act of executive control

    Ben M Crittenden, Daniel J Mitchell, John Duncan
    The default mode network in the brain is activated during the performance of executive-type tasks when a substantial change in cognitive contents is required.
    1. Medicine
    2. Neuroscience

    Recovery of consciousness and cognition after general anesthesia in humans

    George A Mashour, Ben JA Palanca ... Max B Kelz
    Cognitive reconstitution after pharmacologic unconsciousness is an extended process, executive function is more robust than expected, and the healthy human brain is resilient to the effects of deep general anesthesia.
    1. Computational and Systems Biology
    2. Neuroscience

    Myelin dystrophy impairs signal transmission and working memory in a multiscale model of the aging prefrontal cortex

    Sara Ibañez, Nilapratim Sengupta ... Christina M Weaver
    Biologically plausible levels of myelin dystrophy induce substantial working memory impairment in a computational model of brain aging across two spatial and temporal scales.
    1. Neuroscience

    Neural pattern change during encoding of a narrative predicts retrospective duration estimates

    Olga Lositsky, Janice Chen ... Kenneth A Norman
    Judgments of how much time elapsed between two events in a story are predicted by changes in fMRI activity patterns.