The Botryllus schlosseri genome yields insights into the evolution of hematopoiesis.

A normally cytoplasmic deacetylase, Hdac6, localizes to the nucleus in embryonic stem cells, where it regulates the essential Tip60-p400 chromatin remodeling complex.

MLL4 (KMT2D) is a major mammalian H3K4 mono- and di-methyltransferase that is essential for enhancer activation, cell-type-specific gene expression, and cell differentiation.

Schwann cell induced quiescence of mechanosensory progenitor cells is mediated by inhibition of Wnt/β-catenin signaling.

The RNA-binding protein MSI1, which is required for stem cell and cancer cell proliferation in the brain and epithelial tissues, also directly senses the concentration of long non-esterified omega-9 fatty acids.

Sialoside-based pattern recognition by Siglecs directly regulates toll-like receptor signaling and a sialidase inhibitor protects against endotoxemia.

Large flight muscle of Drosophila are made by the regulated amplification of a newly identified stem cell population.

The THAP-domain protein Bip1, along with other proteins Nup98 and RpS8, controls the expression of the protein Pvr, a critical non-cell-autonomous regulator of Drosophila blood progenitor maintenance.

Identifying 1,907 mitochondrial somatic mutations from 1,675 tumor tissues provides new insights into the causes and effects of the mitochondrial genome mutations found in human cancers.

Multipotent cardiac precursors within a population of mesoderm are rapidly fated to specific anatomic locations in the developing mouse heart.