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A new method for in vivo cell-specific profiling of chromatin accessibility reveals local and global chromatin dynamics during the differentiation of neural and gut stem cell lineages.

A systemic hormone controls progenitor fate decisions independent of local fate determining pathways in the adult intestinal stem cell niche of Drosophila melanogaster..

In contrast to growing evidence that juxtracrine signalling accounts for Wnt/Wingless patterning function, Wingless behaves as a released signal in Drosophila renal tubule development, being secreted from the midgut to spread and pattern the proximal tubule.

Bacterial location quantifications highlights how Drosophila melanogaster larvae discriminate bacteria to isolate and later eliminate pathogens in the anterior midgut through coordinated mechanisms involving reactive oxygen species (ROS) and antimicrobial peptides (AMPs).

Left-right asymmetric rotation of the Drosophila hindgut is driven by "cell sliding," a novel cellular behavior induced by chiral cell deformation, in which cells change their position relative to subjacent neighbors as sliding directionally.

The nutrient composition of food alters both the size of gut epithelial cells and the ability of the stem cell niche to control tissue turnover, resulting in changes in size at the organ level.

Atg9 inhibits TOR signaling to regulate cell growth and tissue homeostasis in Drosophila adult midgut.

Functional recapitulation of a likely evolutionary gain in gene expression shows that two genes are sufficient to switch mesoderm cell internalization from stochastic cell ingression to coordinated epithelial invagination.

A retracting gradient of the transcription factor Tailless spatiotemporally patterns the Drosophila tail region by modulating the intrinsic dynamics of a regulatory network involving the timer genes caudal, Dichaete, and odd-paired.