495 results found
    1. Stem Cells and Regenerative Medicine

    The follicle epithelium in the Drosophila ovary is maintained by a small number of stem cells

    Jocelyne Fadiga, Todd G Nystul
    Just 2-4 follicle stem cells maintain each follicle epithelium in the Drosophila ovary, and they reside within a single ring at the anterior edge of the tissue.
    1. Stem Cells and Regenerative Medicine

    Ovaries absent links dLsd1 to HP1a for local H3K4 demethylation required for heterochromatic gene silencing

    Fu Yang et al.
    A Drosophila fertility gene is identified that acts as a linker between HP1a and local H3K4 demethylation during HP1a-mediated gene silencing that is required for ovary development and transposon silencing..
    1. Evolutionary Biology
    2. Genetics and Genomics

    Reproduction: How flies turn food into progeny

    Thomas Flatt
    Sex-optimal diets have different effects on gene expression in female and male flies.
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    1. Evolutionary Biology

    The Natural History of Model Organisms: Insights into mammalian biology from the wild house mouse Mus musculus

    Megan Phifer-Rixey, Michael W Nachman
    Studies of the house mouse Mus musculus have provided important insights into mammalian biology, and efforts to study wild house mice and to create new inbred strains from wild populations have the potential to increase its usefulness as a model system.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Science Forum: Considerations when investigating lncRNA function in vivo

    Andrew R Bassett et al.
    We discuss the methods available to understand lncRNA function in vivo, and highlight important considerations that should be taken into account when designing such experiments.
    1. Neuroscience

    Thermoregulation: How a brain keeps its cool

    Swathi Yadlapalli, Orie T Shafer
    Temperature-sensing neurons in the Drosophila brain cooperate with the central circadian clock to help regulate body temperature.
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    1. Developmental Biology

    Organ Plasticity: Paying the costs of reproduction

    Thomas Flatt
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    1. Developmental Biology
    2. Genetics and Genomics

    Nuclear receptor Ftz-f1 promotes follicle maturation and ovulation partly via bHLH/PAS transcription factor Sim

    Elizabeth M Knapp et al.
    Genetic analyses illustrate the novel requirement of Ftz-f1 and Sim in adult Drosophila ovaries for regulating follicle cell differentiation and ovulation that is likely conserved in mammals.
    1. Neuroscience

    Cre-assisted fine-mapping of neural circuits using orthogonal split inteins

    Haojiang Luan et al.
    A genetic method allows neurons to be individually identified and characterized by combining information about both their developmental origins and their mature patterns of gene expression.
    1. Cell Biology
    2. Developmental Biology

    Protein phosphatase 1 activity controls a balance between collective and single cell modes of migration

    Yujun Chen et al.
    Protein phosphatase 1 activity promotes cohesive collective cell migration by restricting actomyosin contractility to the periphery of the collective and maintaining proper cadherin–catenin complex protein levels at cell–cell junctions.

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