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    1. Cell Biology
    2. Physics of Living Systems

    Interplay of cell dynamics and epithelial tension during morphogenesis of the Drosophila pupal wing

    Raphaël Etournay et al.
    Autonomous patterns of cell contraction in the context of localized apical extracellular matrix constraints specify tissue stresses that reshape the wing epithelium.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Cell-cycle quiescence maintains Caenorhabditis elegans germline stem cells independent of GLP-1/Notch

    Hannah S Seidel, Judith Kimble
    C. elegans germline stem cells become quiescent under starved conditions, and this quiescence maintains the stem cell state even in the absence of GLP-1/Notch signaling, which is otherwise essential for stem cell maintenance.
    1. Neuroscience

    Odor-identity dependent motor programs underlie behavioral responses to odors

    Seung-Hye Jung et al.
    Flies respond to odors by modulating multiple independently modulated motor programs.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Immune genes are hotspots of shared positive selection across birds and mammals

    Allison J Shultz, Timothy B Sackton
    Pathogens, particularly viruses, target the same genes over deep evolutionary time, resulting in shared signatures of positive selection and transcriptional responses at the same genes.
    1. Developmental Biology
    2. Neuroscience

    Morphologic diversity of cutaneous sensory afferents revealed by genetically directed sparse labeling

    Hao Wu et al.
    The first survey of the complete morphologies of nerve endings in the skin of mice has revealed enormous structural diversity.
    1. Cell Biology
    2. Developmental Biology

    Ovulation in Drosophila is controlled by secretory cells of the female reproductive tract

    Jianjun Sun, Allan C Spradling
    Secretory cells in the fruit fly reproductive tract produce secretions that control ovulation through a conserved mechanism that could provide insights into ovarian cancer.
    1. Developmental Biology

    An essential role for maternal control of Nodal signaling

    Pooja Kumari et al.
    Regulation of conserved Nodal factors by a maternal protein ensures that Nodal signaling is repressed until the appropriate time in embryonic development.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages

    Chwee Tat Koe et al.
    A novel complex composed of various components of a chromatin remodeling complex, a chromatin remodeling factor and a transcription factor suppresses the dedifferentiation of intermediate neural progenitors back into neuroblasts in Drosophila.
    1. Stem Cells and Regenerative Medicine

    Wnt signaling-mediated redox regulation maintains the germ line stem cell differentiation niche

    Su Wang et al.
    Wnt signaling regulates cellular redox in the germline stem cell differentiation niche via a novel regulatory mechanism, thereby controlling germ line stem cell progeny differentiation.
    1. Neuroscience

    A network of autism linked genes stabilizes two pools of synaptic GABAA receptors

    Xia-Jing Tong et al.
    Mobile and immobile GABAA receptors in the C. elegans neuromuscular synapse are stabilized by two distinct protein scaffolds.