A single-cell RNA-seq study examining gene expression profiles in neurons that underlie Drosophila reproductive behaviors shows males and females build sex-specific behaviors at the molecular-genetic level by overlaying sex-specific information on core gene expression networks.

Prothoracicotropic hormone and ecdysone belonging to the insect PG axis modulate virgin female sexual receptivity.

The newly characterized activity regulating neuropeptide encoding gene Spar is a transcriptional target of the Jeb/Alk receptor tyrosine kinase signaling pathway in the Drosophila nervous system.

Connectomic, optogenetic, and high-throughput behavioral analyses identify a descending neuron in the fruit fly larval brain that modifies the timing of nociception-induced rolling.

The catalytic activity of a Drosophila neprilysin is critical to proper insulin expression and food intake by regulating homeostasis of distinct signaling peptides.

Dsk-expressing neurons function downstream of a subset of P1 neurons to control fighting behavior.

Descending inhibition of nociception from the brain has been identified in Drosophila larvae, for the first time in non-mammalian organisms.