838 results found
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    A novel GTP-binding protein–adaptor protein complex responsible for export of Vangl2 from the trans Golgi network

    Yusong Guo, Giulia Zanetti, Randy Schekman
    The ability of epithelial cells to distinguish between domains on opposing cell surfaces within a tissue, a property known as planar cell polarity, relies on proteins and protein complexes directing the traffic of signaling proteins to specific locations on the cell surface membrane.
    1. Cell Biology
    2. Developmental Biology

    Mitotic spindle scaling during Xenopus development by kif2a and importin α

    Jeremy D Wilbur, Rebecca Heald
    An interaction between two proteins enables the spindle—the structure that segregates chromosome pairs during mitosis—to change size as cells divide.
    1. Neuroscience

    Kinesin-1 regulates dendrite microtubule polarity in Caenorhabditis elegans

    Jing Yan, Dan L Chao ... Kang Shen
    A cellular motor protein helps to ensure that microtubules are oriented correctly within neuronal dendrites
    1. Structural Biology and Molecular Biophysics

    Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization

    Siyang Sun, Ye Xiang ... Michael G Rossmann
    Electron cryo-microscopy has been used to determine the structure of Chikungunya virus-like particles and to provide new insights into their interactions with four different antibodies.
    1. Cell Biology
    2. Developmental Biology

    Ovulation in Drosophila is controlled by secretory cells of the female reproductive tract

    Jianjun Sun, Allan C Spradling
    Secretory cells in the fruit fly reproductive tract produce secretions that control ovulation through a conserved mechanism that could provide insights into ovarian cancer.
    1. Cell Biology

    ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast

    Andrew Murley, Laura L Lackner ... Jodi Nunnari
    Sites at which mitochondria contact the endoplasmic reticulum co-localize the replication of mitochondria and their DNA to help ensure that DNA is distributed appropriately between the newly formed organelles in cells.
    1. Cell Biology

    Intraflagellar transport drives flagellar surface motility

    Sheng Min Shih, Benjamin D Engel ... Ahmet Yildiz
    The transport of proteins along flagellar microtubules generates the force that enables flagella to propel cells across surfaces.
    1. Cell Biology
    2. Neuroscience

    Dynamin phosphorylation controls optimization of endocytosis for brief action potential bursts

    Moritz Armbruster, Mirko Messa ... Timothy A Ryan
    The recycling of transmitter vesicles at synapses shows calcium-dependent regulation that depends on the phosphorylation status of an enzyme called dynamin.
    1. Cell Biology

    Single molecule imaging reveals a major role for diffusion in the exploration of ciliary space by signaling receptors

    Fan Ye, David K Breslow ... Maxence V Nachury
    Membrane receptor proteins move through primary cilia largely by passive diffusion rather than by active intraflagellar transport.
    1. Cell Biology
    2. Neuroscience

    Neuroscience: Endocytosis gets in tune with action potential bursts

    Melissa A Herman, Christian Rosenmund
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