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Severely immunodeficient B2m-NOG mice transplanted with human peripheral blood mononuclear cells from multiple sclerosis patients partially reproduce disease immunopathology and represent novel experimental models for studying human immune responses to the central nervous system in a rapid and personalized manner.

The identification of 31 neuropeptide GPCRs in the sea anemone Nematostella vectensis provides a rich resource to study peptidergic signaling in cnidarians and suggests that cnidarian and bilaterian peptidergic systems diversified independent from each other from a few ancestral systems.

A novel FRET approach suggests that the intracellular termini of acid-sensing ion channel 1a do not form a complex at rest requiring a new hypothesis for ASIC1a involvement in stroke.

The largest federally qualified health center in Massachusetts was able to improve cervical cancer screening rates during the COVID-19 pandemic by creating clinical sessions devoted only to screenings.

Mouse models with specific presynaptic knockout demonstrate that Rim1α is subjected to threonine phosphorylation by a novel EPAC-PKCε module, which is essential to presynaptic transmitter release, required for the induction of presynaptic LTP, and critical for motor learning.

Tie1 is a binding partner for Svep1 in zebrafish and humans, and both genes (but not Tie2) are required during zebrafish lymphangiogenesis especially for the facial lymphatics, which in part develop independent of Vegfc.

The thymic selection of the human T-cell receptor repertoire releases polyspecific receptors with the ability to recognize and respond to peptides from unrelated viruses.

Mapping the ion permeation pathway within the internal pore of ATP-activated P2X receptor channels.