The transcription factor ERG recruits the PRMT5 enzyme to methylate the androgen receptor, presenting a post-translational regulatory mechanism that could be therapeutically exploited to control cell proliferation.
Alpha EEG oscillations emerge at 4 months of age during sevoflurane general anesthesia, and unlike in adults, have a widespread spatial distribution that likely reflects differences in brain development.
The ion channel ppk301 is required for the evaluation of water purity during egg-laying, which promotes offspring survival in the arboviral vector mosquito Aedes aegypti.
Mental codes that track our position within complex, behavioral sequences, have been hard to pin down empirically, but can be identified and traced over time using oscillatory EEG activity.
Ig domain family members DIP-alpha and Dpr10 are required in a subset of Drosophila leg motor neurons and muscles, respectively, to establish their fine terminal branching pattern and synapses.
Direct measure of neural and hemodynamic activity in the developing human brain shows that the insula is a major source of transient bursting events that are critical for cortical maturation.
The kinase that controls maternal mRNA translation is regulated by phosphorylation of its activating subunit to restrict kinase activity to the developmental window between meiosis completion and early embryogenesis.
Quantitative microscopy and theory show that the size of Xenopus laevis egg extract spindles is controlled by a spatially-regulated autocatalytic growth mechanism driven by microtubule-stimulated microtubule nucleation.
