2,118 results found
  1. August 2015

    Episode 22: August 2015

    In this episode we hear about cancer, dengue fever, sperm DNA and neurons that are sensitive to magnetic fields.
  2. December 2014

    Episode 16: December 2014

    In this episode we hear about reproducibility, drug resistance, cells without walls, gene transfer, interspecies signalling, and stem cells.
    1. Developmental Biology
    2. Plant Biology

    Quantitative analysis of auxin sensing in leaf primordia argues against proposed role in regulating leaf dorsoventrality

    Neha Bhatia et al.
    Top-bottom patterning of leaves is not specified by an asymmetry in the distribution of the plant hormone auxin, in contrast to a previous proposal.
    1. Neuroscience

    Elementary sensory-motor transformations underlying olfactory navigation in walking fruit-flies

    Efrén Álvarez-Salvado et al.
    A high-throughput behavioral paradigm and computational modeling are used to decompose olfactory navigation in walking Drosophila melanogaster into a set of quantitative relationships between sensory input and motor output.
    1. Cancer Biology

    Mitochondrial genetic diversity, selection and recombination in a canine transmissible cancer

    Andrea Strakova et al.
    Genetics of a canine transmissible tumour show how the world’s oldest cancer “metastasised” through the global dog population – and captured, maintained and rearranged its mitochondrial DNA along the way.
    1. Developmental Biology
    2. Neuroscience

    Cis and trans RET signaling control the survival and central projection growth of rapidly adapting mechanoreceptors

    Michael S Fleming et al.
    Cis and trans activation of the receptor tyrosine kinase RET lead to similar biological outcomes in rapidly adapting mechanoreceptors in vivo.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Electrostatic lateral interactions drive ESCRT-III heteropolymer assembly

    Sudeep Banjade et al.
    ESCRT-III heteropolymers utilize non-specific lateral electrostatic interactions to recognize one another, which may enable the polymers to slide along one another and adapt to different curvatures.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    A model symbiosis reveals a role for sheathed-flagellum rotation in the release of immunogenic lipopolysaccharide

    Caitlin A Brennan et al.
    Both beneficial and pathogenic bacteria can use their sheathed flagella during host colonization as a novel toxin-/signal-delivery mechanism.
    1. Structural Biology and Molecular Biophysics
    2. Computational and Systems Biology

    A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation

    Emily F Ruff et al.
    Phosphorylation of Aurora A does not trigger a population shift to the active state as previously thought, but instead switches the kinase on by tuning the structure and dynamics of a dynamically sampled subpopulation.
    1. Developmental Biology
    2. Neuroscience

    Tau and spectraplakins promote synapse formation and maintenance through Jun kinase and neuronal trafficking

    Andre Voelzmann et al.
    A novel regulatory cascade downstream of Tau and spectraplakins ensures that synaptic proteins are delivered to axonal terminals in the developing and ageing brain, providing potential explanations for precocious synapse loss in dementias.

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