A plant autophagy pathway transports chloroplast stroma and envelope components into the vacuole through the division and encapsulation of the site of chloroplasts that is associated with developing autophagosome.
Miguel Martinez-Ara, Federico Comoglio, Bas van Steensel
A high-throughput enhancer-enhancer-promoter reporter assay indicates that pairs of enhancers generally activate promoters in a near-additive manner, and that promoters transform their collective effect non-linearly.
Identification of central neural circuits and sensory pathways underlying social-sexual modulation of sperm ejection in female Drosophila unraveled cryptic mate choice, a mechanism of post-copulatory sexual selection.
MYCN and TFIIIC exert a censoring function during early transcription, limiting the accumulation of inactive RNAPII at the promoter and facilitating promoter-proximal degradation of nascent RNA.
Studies in murine model identify hepatic Rela-Stat3 network as a potential driver of gut inflammation and a novel therapeutic target for inflammatory bowel disease, offering new insights into liver-gut crosstalk.
Christin Krause, Jan H Britsemmer ... Henriette Kirchner
The liver microRNA transcriptome of humans with type 2 diabetes and obesity is analyzed for the first time and compared with diet-induced obesity in mice.
