Applying deep learning technology for the large-scale curation of symptoms from unstructured EHR clinical notes accurately predicts the differential signals of COVID-19 diagnosis over the week preceding typical PCR testing.

Ubiquitin ligase adaptors target the selective clearance of misfolded plasma membrane proteins.

Direct reprogramming of somatic cells to an inner ear sensory hair cell-like state provides an experimental platform to identify causes and treatments for hair cell loss and hearing deficits.

Inhibition of activity in the right frontal eye fields reduces the amplifying effect of gaze in value-based choice.

Zebra finches are capable of overt vocal planning, but to reach a distant vocal target beyond the range of recently produced pitch requires both practice and auditory feedback.

Building on previous work (Tang et al., 2015), novel ESCRT-III subunit Snf7 auto-activation mutants are used to reveal two parallel ubiquitin-dependent pathways during multivesicular endosome biogenesis.

Single-cell transcriptomic analysis defines hair cell and supporting cell types in the zebrafish inner ear, and reveals homologies with cells in the mammalian ear.

When making two decisions about one object, two streams of information can be acquired in parallel but must be incorporated into the two decisions serially, consistent with a central bottleneck.

Genetic analyses reveal the importance of dynamic protein processing at the apical cell membrane in response to forces damaging cell membranes during tube expansion in tubular organs.

The lysosome membrane is a new functional location for the ESCRTs in yeast.