3,687 results found
    1. Developmental Biology

    Pilot study of large-scale production of mutant pigs by ENU mutagenesis

    Tang Hai et al.
    ENU mutagenesis in pigs is an efficient strategy to introduce mutations at the whole-genome level and mutants have been generated on a large scale for agricultural production and biomedical research.
    1. Biochemistry and Chemical Biology
    2. Immunology and Inflammation

    Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios+ T cells and autoantibodies

    Stephen R Daley et al.
    A single point mutation in a Ras activator leads to aberrant constitutive mTOR signaling in peripheral T cells that consequently accumulate as abnormal T helper cells and stimulate the production of autoantibodies by B cells.
    1. Cell Biology
    2. Neuroscience

    Hypoxia: Adapt or avoid

    Ganesh K Kumar
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    1. Neuroscience

    Axon Growth: How to survive a nerve-wracking journey

    Andrea Yung, Lisa V Goodrich
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    1. Evolutionary Biology

    Experimental Evolution: A sticky solution

    David Gresham
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    1. Ecology
    2. Evolutionary Biology

    The Natural History of Model Organisms: Advancing biology through a deeper understanding of zebrafish ecology and evolution

    David M Parichy
    The zebrafish is a premier model organism for biomedical research, with a rich array of tools and genomic resources, and combining these with a fuller appreciation of wild zebrafish ecology could greatly extend its utility in biological research.
    1. Computational and Systems Biology

    Point of View: Data science for the scientific life cycle

    Daphne Ezer, Kirstie Whitaker
    Each stage of the scientific life cycle stands to benefit from the introduction of data science techniques.
    1. Stem Cells and Regenerative Medicine

    Quiescence: Quantitative differences, qualitative outcomes

    Giulia Pollarolo, Cayetano Gonzalez
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    1. Genetics and Genomics
    2. Neuroscience

    Mosquitos: The taste of water

    W Daniel Tracey
    Female mosquitos require a specific ion-channel protein to sense the presence of fresh water in which they can lay their eggs.
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